Therapeutic Instrumental Music Performance With Sensory-Enhanced Motor Imagery in Chronic Post-Stroke Rehabilitation
Efficacy of Therapeutic Instrumental Music Performance With Sensory-Enhanced Motor Imagery in Improving Therapeutic Outcomes for Individuals With Chronic Post-Stroke Hemiparesis
1 other identifier
interventional
30
1 country
1
Brief Summary
Research has shown that music engages the brain bilaterally throughout cortical and subcortical regions, accessing extended sensorimotor, cognitive and affective networks. This research explores the hypothesis that use of these shared neural networks allows neurologic music therapy interventions targeting upper extremity motor control to promote plasticity and functional improvements in persons recovering from a cerebrovascular accident. The potential therapeutic benefits of these interventions on attentional processes and affective responding will also be examined.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable stroke
Started Jul 2017
Typical duration for not_applicable stroke
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 20, 2017
CompletedFirst Submitted
Initial submission to the registry
August 7, 2017
CompletedFirst Posted
Study publicly available on registry
August 11, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 5, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
September 5, 2019
CompletedSeptember 16, 2019
September 1, 2019
2.1 years
August 7, 2017
September 11, 2019
Conditions
Outcome Measures
Primary Outcomes (2)
Changes from baseline in Wolf Motor Function Test
Measures upper extremity motor ability through timed and functional tasks.
Baseline 1, Baseline 2 (1 week later), Post intervention of 4 weeks
Changes from baseline in Fugl-Meyer Assessment Upper Extremity
Performance based measure assessing motor capacity.
Baseline 1, Baseline 2 (1 week later), Post intervention of 4 weeks
Secondary Outcomes (6)
Motor Activity Log
Baseline 1, Baseline 2 (1 week later), Post intervention of 4 weeks
Trunk Impairment Scale
Baseline 1, Baseline 2 (1 week later), Post intervention of 4 weeks
Multiple Affect Adjective Check List-Revised
Baseline 1, Baseline 2 (1 week later), Post intervention of 4 weeks
General Self-Efficacy Scale
Baseline 1, Baseline 2 (1 week later), Post intervention of 4 weeks
Digit Span
Baseline 1, Baseline 2 (1 week later), Post intervention of 4 weeks
- +1 more secondary outcomes
Study Arms (3)
Therapeutic Instrumental Music Performance
EXPERIMENTALTherapeutic Instrumental Music Performance is a Neurologic Music Therapy technique in which selection of instruments, spatial configurations and sequences for playing are designed to facilitate retraining of movement patterns used in everyday life. Participants will receive nine individual forty-five minute sessions of Therapeutic Instrumental Music Performance, three sessions per week.
Therapeutic Performance with Sensory-Enhanced Motor Imagery
EXPERIMENTALParticipants will receive nine individual sessions, three times per week: thirty minutes of Therapeutic Instrumental Music Performance, followed by fifteen minutes of sensory-enhanced motor imagery. During sensory-enhanced motor imagery, participants will listen to a metronome set to their preferred pace for previously practised movements while engaging in motor imagery.
Therapeutic Performance with Motor Imagery
EXPERIMENTALParticipants will receive nine individual sessions, three times per week: thirty minutes of Therapeutic Instrumental Music Performance, followed by fifteen minutes of motor imagery. Motor imagery will involve mental practice of previous movement exercises.
Interventions
Participants will play a variety of instruments (acoustic and electronic) to facilitate retraining of everyday functional movements.
Participants will listen to a metronome set to their preferred pace for previously practised movements while engaging in motor imagery.
Participants will engage in motor imagery of previously practised movements.
Eligibility Criteria
You may qualify if:
- hemiparesis following a unilateral stroke (hemorrhagic or ischemic), sustained more than 6 months prior, with at least minimal volitional movement of the affected limb
- permission from a physician to participate in an upper extremity rehabilitation program, including confirmation that the following disorders are not present: rheumatoid arthritis, upper extremity fracture, apraxia, neuropathy, somatosensory impairment
- adequate language comprehension and neurocognitive function to understand and follow simple instructions
You may not qualify if:
- currently enrolled in an upper extremity rehabilitation program or another upper extremity study
- comorbid neurological disorder (e.g. multiple sclerosis, Parkinson's disease)
- evidence of perceptual or cognitive impairment; e.g., unilateral spatial neglect, significant hearing impairment, Montreal Cognitive Assessment score of 25 or less
- presence of aphasia
- injections for spasticity within three months of participation
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Faculty of Music, University of Toronto
Toronto, Ontario, M5S2C5, Canada
Related Publications (1)
Loria T, de Grosbois J, Haire C, Vuong V, Schaffert N, Tremblay L, Thaut MH. Music-based intervention drives paretic limb acceleration into intentional movement frequencies in chronic stroke rehabilitation. Front Rehabil Sci. 2022 Oct 3;3:989810. doi: 10.3389/fresc.2022.989810. eCollection 2022.
PMID: 36262914DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Michael Thaut, PhD
University of Toronto
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- PhD Candidate
Study Record Dates
First Submitted
August 7, 2017
First Posted
August 11, 2017
Study Start
July 20, 2017
Primary Completion
September 5, 2019
Study Completion
September 5, 2019
Last Updated
September 16, 2019
Record last verified: 2019-09
Data Sharing
- IPD Sharing
- Will not share