NCT03243682

Brief Summary

compare the outcomes of SWL for renal and upper lumbar ureteric stones using the alternating bidirectional approach versus the standard approach.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
240

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Sep 2016

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2016

Completed
11 months until next milestone

First Submitted

Initial submission to the registry

July 29, 2017

Completed
11 days until next milestone

First Posted

Study publicly available on registry

August 9, 2017

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2018

Completed
Last Updated

August 9, 2017

Status Verified

July 1, 2017

Enrollment Period

1.5 years

First QC Date

July 29, 2017

Last Update Submit

August 7, 2017

Conditions

Keywords

Shock wave lithotripsyBidirectionalStones

Outcome Measures

Primary Outcomes (1)

  • stone free rate three months after the last session

    residual less than 4 mm by non-contrast computerized tomography scan (NCCT)

    18 months

Secondary Outcomes (1)

  • severity of complications after SWL in both groups

    18 months

Study Arms (2)

Bidirectional Shock Wave Lithotripsy

ACTIVE COMPARATOR

alternating bidirectional (under and over table) approach

Procedure: Bidirectional Shock Wave Lithotripsy

Standard Shock Wave Lithotripsy

ACTIVE COMPARATOR

standard unidirectional approach

Procedure: Standard Shock Wave Lithotripsy

Interventions

the alternating bidirectional (under and over table) approach during SWL for renal and upper lumbar ureteric stones

Also known as: Bidirectional SWL
Bidirectional Shock Wave Lithotripsy

the standard unidirectional approach during SWL for renal and upper lumbar ureteric stones

Also known as: Standard SWL
Standard Shock Wave Lithotripsy

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patient criteria:
  • Ability to give informed consent.
  • Normal laboratory profile as regarding serum creatinine, liver function, platelets count and prothrombin time.
  • Stone criteria:
  • Single renal stone less than two cm or upper lumbar ureteric stone less than one cm.
  • Radio-opaque stones.

You may not qualify if:

  • Bleeding tendency.
  • Poor kidney function.
  • Pregnancy.
  • Abdominal aortic aneurysm.
  • Indwelling DJ ureteric stent or percutaneous nephrostomy tube (PCN).
  • Congenital anomalies of the urinary tract.
  • Untreated urinary tract infection.
  • Obstructed urinary tract distal to the stone.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Urology and Nephrology center

Al Mansurah, 35516, Egypt

Location

Related Publications (1)

  • Hegazy M, El-Assmy A, Ali-El-Dein B, Sheir KZ. The alternating bidirectional versus the standard approach during shock wave lithotripsy for upper lumbar ureteric stones: a randomized controlled trial. World J Urol. 2021 Jan;39(1):247-253. doi: 10.1007/s00345-020-03148-5. Epub 2020 Mar 23.

MeSH Terms

Conditions

Urologic DiseasesKidney CalculiUrinary CalculiCalculi

Condition Hierarchy (Ancestors)

Female Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesNephrolithiasisKidney DiseasesUrolithiasisPathological Conditions, AnatomicalPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD

Study Record Dates

First Submitted

July 29, 2017

First Posted

August 9, 2017

Study Start

September 1, 2016

Primary Completion

March 1, 2018

Study Completion

March 1, 2018

Last Updated

August 9, 2017

Record last verified: 2017-07

Locations