Effectiveness of Contemporary Knee Arthroplasty in Working-age Patients
1 other identifier
interventional
250
0 countries
N/A
Brief Summary
The aim of our study was to assess the effectiveness of contemporary knee arthroplasty in working-age patients (\< 65 years) by conducting a prospective cohort study with 2-year follow up. Outcomes were measured comprehensively using various patient-reported outcome measures (PROMs) to provide information on the effect of knee arthroplasty on pain, satisfaction, physical activity, activities of daily living, and quality of life.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable knee-osteoarthritis
Started Mar 2012
Longer than P75 for not_applicable knee-osteoarthritis
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2012
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 30, 2014
CompletedStudy Completion
Last participant's last visit for all outcomes
November 1, 2016
CompletedFirst Submitted
Initial submission to the registry
July 26, 2017
CompletedFirst Posted
Study publicly available on registry
July 28, 2017
CompletedJuly 28, 2017
July 1, 2017
2.7 years
July 26, 2017
July 27, 2017
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Effectiveness of contemporary knee arthroplasty in working-age patients
PROMs
2 years
Study Arms (1)
working age patients
OTHERProspective cohort of 250 patients.
Interventions
Eligibility Criteria
You may qualify if:
- Age 65 or less and
- Scheduled for either TKA or unicondylar knee arthroplasty (UKA)
You may not qualify if:
- rheumatoid arthritis or other inflammatory diseases
- unwilling to provide informed consent
- physical, mental, or neurological conditions that could comprise the patient´s ability and compliance with postoperative rehabilitation and follow-up (e.g., drug or alcohol abuse, serious mental illness, general neurological conditions such as Parkinson's disease, multiple sclerosis (MS), etc.)
- known sensitivity to materials in the devices.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Leppanen S, Niemelainen M, Huhtala H, Eskelinen A. Mild knee osteoarthritis predicts dissatisfaction after total knee arthroplasty: a prospective study of 186 patients aged 65 years or less with 2-year follow-up. BMC Musculoskelet Disord. 2021 Aug 5;22(1):657. doi: 10.1186/s12891-021-04543-8.
PMID: 34353317DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 26, 2017
First Posted
July 28, 2017
Study Start
March 1, 2012
Primary Completion
October 30, 2014
Study Completion
November 1, 2016
Last Updated
July 28, 2017
Record last verified: 2017-07
Data Sharing
- IPD Sharing
- Will not share