Evaluation of a Computer Game Based Rehabilitation System for Assessment and Treatment of Balance and Gait Impairments in Individuals With Parkinson's Disease.

NCT03232996 | Completed

• 1 other identifier: H2017:225
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Examining the feasibility and acceptability of the computer game based rehabilitation system for improving balance, gait and executive function in individuals with PD. This will involve a pilot case series intervention study of individuals with PD will be conducted.

Conditions

Parkinson Disease; Parkinson

Keywords

Balance; Gait

Outcome Measures

Primary Outcomes (2)

• Dynamic Standing Balance

  The following tasks will be performed for 45 seconds while standing on a sponge pad; a) eyes open (EO), i.e. single task balance condition, and then b) performing the computer gaming activities (i.e. DT balance conditions). A force sensor array (FSA) pressure-sensing mat (Vista Medical Ltd., Manitoba, Canada) will be used to record vertical foot pressures and thus to compute center of foot pressure (COP) migration.

  Change from baseline Dynamic standing balance at 8 weeks

• Gait Assessment

  The participant will first be asked to walk on the treadmill at his/her comfortable speed for 3 minutes to acclimate with the treadmill prior to testing. After a rest period of 2 minutes they will be asked to walk for 1 minute under the following conditions; a) walk only or single task condition and b) walking while performing the computer gaming tasks (DT walking condition). The treadmill instrumented with a pressure mat (Vista Medical, CA) will be used to record vertical foot contact forces and used to compute spatial-temporal gait variables. Participants walked for 5 minutes to acclimate to the treadmill prior to testing.

  Change from baseline spatio-temporal gait variables at 8 weeks.

Secondary Outcomes (1)

• Unified Parkinson Disease Rating Scale (UPDRS)

  Change from baseline "Final UPDRS scores" at 8 weeks.

Study Arms (1)

Experimental Group

EXPERIMENTAL

Computer Game based balance and walk rehabilitation

Other: Computer game based balance and walking rehabilitation for individuals with Parkinson's Disease

Interventions

Computer game based balance and walking rehabilitation for individuals with Parkinson's Disease OTHER

All the participants will take part in an 8 week (twice per week) computer game based exercise program for dual task balance and dual task walk training. Participants will be standing in front of LED monitor. They will be asked to wear a head band which will be instrumented with motion sense mouse. Thus, hands-free head rotations will be used to interact with the computer games selected for the DT rehabilitation program. Participants will play few interactive computer games during - Normal standing (fixed surface), Standing on a compliant sponge pad and then while walking on a treadmill.

Experimental Group

Eligibility Criteria

• Age: 55 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Diagnosed with idiopathic PD, defined by the UK Brain Bank criterion
• In disease stage 2 - 3 (classified by Hoehn and Yahr scale)
• Montreal cognitive assessment (MoCA) scores to be 25 or higher
• Able to walk at least 50 meters without any assistance.

You may not qualify if:

• Any psychiatric co-morbidity
• Clinically diagnosed dementia or any clinically significant cognitive impairments.
• History of neurological disorder other than PD, which could affect the performance of the participant
• Orthopedic disorders which can affect gait or balance for the participant
• Any unstable medical condition which majorly includes cardiovascular impairments.

Sponsors & Collaborators

• University of Manitoba: lead

Study Sites (1)

College of Rehabilitation Sciences, University of Manitoba

Winnipeg, Manitoba, R3E 0T6, Canada

Location

Related Publications (1)

• Bhatt M, Mahana B, Ko JH, Kolesar TA, Kanitkar A, Szturm T. Computerized Dual-Task Testing of Gait Visuomotor and Cognitive Functions in Parkinson's Disease: Test-Retest Reliability and Validity. Front Hum Neurosci. 2021 Jul 15;15:706230. doi: 10.3389/fnhum.2021.706230. eCollection 2021.

  PMID: 34335213 DERIVED

MeSH Terms

Conditions

Parkinson Disease

Condition Hierarchy (Ancestors)

Parkinsonian Disorders; Basal Ganglia Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Movement Disorders; Synucleinopathies; Neurodegenerative Diseases

Study Officials

• Tony Szturm, Ph.D.

  Professor

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Single Group Assignment

Study Record Dates

• First Submitted: July 24, 2017
• First Posted: July 28, 2017
• Study Start: November 1, 2017
• Primary Completion: April 30, 2019
• Study Completion: August 1, 2019
• Last Updated: March 25, 2020

Record last verified: 2018-10

Locations

CA (1)