NCT03230461

Brief Summary

Optimal chest compression depth during CPR is 4.56cm which is at variance with the current guidelines of 5.0-6.0cm. A change in guidelines is only worthwhile if healthcare professionals can accurately judge a subtle reduction in chest compression depth during CPR by a relatively small amount.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Oct 2016

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2016

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

July 21, 2017

Completed
5 days until next milestone

First Posted

Study publicly available on registry

July 26, 2017

Completed
12 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 7, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 7, 2017

Completed
Last Updated

August 9, 2017

Status Verified

August 1, 2017

Enrollment Period

10 months

First QC Date

July 21, 2017

Last Update Submit

August 8, 2017

Conditions

Keywords

CPRBasic life support

Outcome Measures

Primary Outcomes (1)

  • Compression to target window depth

    Mean compression depth

    Two minutes

Secondary Outcomes (1)

  • Compression to target rate

    Two minutes

Study Arms (3)

Target compression depth 4.0-5.0 cm

EXPERIMENTAL

The rescuer is asked to perform two minutes of chest compressions on a manikin, aiming to compress to the target depth at a rate of 100-120/min

Behavioral: Compression depth

Target compression depth 4.5-5.5 cm

EXPERIMENTAL

The rescuer is asked to perform two minutes of chest compressions on a manikin, aiming to compress to the target depth at a rate of 100-120/min

Behavioral: Compression depth

Target compression depth 5.0-6.0 cm

EXPERIMENTAL

The rescuer is asked to perform two minutes of chest compressions on a manikin, aiming to compress to the target depth at a rate of 100-120/min

Behavioral: Compression depth

Interventions

Target compression depth 4.0-5.0 cmTarget compression depth 4.5-5.5 cmTarget compression depth 5.0-6.0 cm

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • NHS professionals (staff or students), who have successfully completed a hospital-accredited basic life support (BLS) course, including a practical CPR component.

You may not qualify if:

  • Pregnancy, significant medical illness or injury that would impair delivery of chest compressions

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital Southampton

Southampton, Hampshire, SO16 6YD, United Kingdom

Location

MeSH Terms

Conditions

Heart Arrest

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular Diseases

Study Officials

  • Charles Deakin, MD

    University Hospital Southampton NHS Foundation Trust

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Masking Details
Participants and researchers are blinded to the actual depth achieved during each CPR run.
Purpose
TREATMENT
Intervention Model
SEQUENTIAL
Model Details: Prospective, randomised.
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 21, 2017

First Posted

July 26, 2017

Study Start

October 1, 2016

Primary Completion

August 7, 2017

Study Completion

August 7, 2017

Last Updated

August 9, 2017

Record last verified: 2017-08

Locations