NCT03222999

Brief Summary

This study will evaluated the epidemiology and the outcomes of patients suffering out-of-hospital cardiac arrest with presumed cardiac etiology in Korea.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30,000

participants targeted

Target at P75+ for all trials

Timeline
32mo left

Started Oct 2015

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress80%
Oct 2015Dec 2028

Study Start

First participant enrolled

October 1, 2015

Completed
1.8 years until next milestone

First Submitted

Initial submission to the registry

July 6, 2017

Completed
13 days until next milestone

First Posted

Study publicly available on registry

July 19, 2017

Completed
11.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2028

Last Updated

March 6, 2025

Status Verified

March 1, 2025

Enrollment Period

13.3 years

First QC Date

July 6, 2017

Last Update Submit

March 4, 2025

Conditions

Out-of-Hospital Cardiac Arrest

Keywords

Out-of-Hospital Cardiac Arrest

Outcome Measures

Primary Outcomes (1)

  • Survival at 6 month

    Patients will be followed upon hospital discharge and up to 6 month.

    6 months after cardiac arrest

Secondary Outcomes (1)

  • Good neurological recovery at 6 month

    6 months after cardiac arrest

Interventions

No intervention plannedOTHER

No intervention planned

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

EMS treated OHCA who visits study participating ED

You may qualify if:

  • OHCA patients who were transported to participating emergency department (ED) by emergency medical service with resuscitation efforts and whose arrest was identified as a presumed cardiac etiology by emergency physicians in ED.

You may not qualify if:

  • OHCA with terminal illness documented by medical record, under hospice care, with pregnancy, with pre-documented 'Do Not Resuscitate' card
  • OHCA of definite non-cardiac etiology, including trauma, drowning, poisoning, burn, asphyxia, or hanging

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Korean Cardiac Arrest Resuscitation Consortium

Seoul, 03080, South Korea

RECRUITING

Related Publications (7)

  • Choi A, Park I, You JS, Chung SP, Park YS. Non-Linear Relationship Between Alcohol Consumption and Neurological Outcomes in Patients With Out-of-Hospital Cardiac Arrest Presenting to the Emergency Department. J Korean Med Sci. 2025 Jun 2;40(21):e96. doi: 10.3346/jkms.2025.40.e96.

    PMID: 40461141DERIVED

  • Lee H, Oh J, Choi HJ, Shin H, Cho Y, Lee J. The Incidence and Outcomes of Out-of-Hospital Cardiac Arrest During the COVID-19 Pandemic in South Korea: Multicenter Registry Study. JMIR Public Health Surveill. 2024 Jun 24;10:e52402. doi: 10.2196/52402.

    PMID: 38913998DERIVED

  • Ko BS, Kim YJ, Han KS, Jo YH, Shin J, Park I, Kang H, Lim TH, Hwang SO, Kim WY. Association between the number of prehospital defibrillation attempts and a sustained return of spontaneous circulation: a retrospective, multicentre, registry-based study. Emerg Med J. 2023 Jun;40(6):424-430. doi: 10.1136/emermed-2021-212091. Epub 2023 Apr 6.

    PMID: 37024298DERIVED

  • Jeong D, Lee GT, Park JE, Chang H, Kim T, Cha WC, Yoon H, Hwang SY, Shin TG, Sim MS, Jo I, Lee SH, Shin SD, Choi JH. Extracorporeal Life-support for Out-of-hospital Cardiac Arrest: A Nationwide Multicenter Study. Shock. 2022 May 1;57(5):680-686. doi: 10.1097/SHK.0000000000001924. Epub 2022 Mar 10.

    PMID: 35271541DERIVED

  • Kim SJ, Kim HS, Hwang SO, Jung WJ, Roh YI, Cha KC, Shin SD, Song KJ; Korean Cardiac Arrest Research Consortium (KoCARC) Investigators. Ionized calcium level at emergency department arrival is associated with return of spontaneous circulation in out-of-hospital cardiac arrest. PLoS One. 2020 Oct 12;15(10):e0240420. doi: 10.1371/journal.pone.0240420. eCollection 2020.

    PMID: 33045006DERIVED

  • Yoon JC, Kim YJ, Ahn S, Jin YH, Lee SW, Song KJ, Shin SD, Hwang SO, Kim WY; Korean Cardiac Arrest Research Consortium KoCARC. Factors for modifying the termination of resuscitation rule in out-of-hospital cardiac arrest. Am Heart J. 2019 Jul;213:73-80. doi: 10.1016/j.ahj.2019.04.003. Epub 2019 May 3.

    PMID: 31129440DERIVED

  • Lee DE, Lee MJ, Ahn JY, Ryoo HW, Park J, Kim WY, Shin SD, Hwang SO; Korean Cardiac Arrest Research Consortium (KoCARC). New Termination-of-Resuscitation Models and Prognostication in Out-of-Hospital Cardiac Arrest Using Electrocardiogram Rhythms Documented in the Field and the Emergency Department. J Korean Med Sci. 2019 May 6;34(17):e134. doi: 10.3346/jkms.2019.34.e134.

    PMID: 31050224DERIVED

MeSH Terms

Conditions

Out-of-Hospital Cardiac Arrest

Condition Hierarchy (Ancestors)

Heart ArrestHeart DiseasesCardiovascular Diseases

Study Officials

  • Sung-Pil Chung, MD, PhD

    Korean Cardiac Arrest Resuscitation Consortium

    STUDY CHAIR

Central Study Contacts

KoCARC Coordination Center

CONTACT

82-2-2072-4052kocarc_cc@naver.com

Yeongho Choi, MD

CONTACT

82-10-4657-9113d2uk87@gmail.com

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Target Duration
6 Months
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Study Chair

Study Record Dates

First Submitted

July 6, 2017

First Posted

July 19, 2017

Study Start

October 1, 2015

Primary Completion (Estimated)

December 31, 2028

Study Completion (Estimated)

December 31, 2028

Last Updated

March 6, 2025

Record last verified: 2025-03

Locations

KR(1)