NCT03220269

Brief Summary

RIAC - An Observational, Prospective, Multi-centre, Study of Epidemiology, Treatment, and Outcome of Cardiac Arrest in Italy.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
8,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Oct 2014

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2014

Completed
2.7 years until next milestone

First Submitted

Initial submission to the registry

June 22, 2017

Completed
26 days until next milestone

First Posted

Study publicly available on registry

July 18, 2017

Completed
2.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 30, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 30, 2019

Completed
Last Updated

July 18, 2017

Status Verified

July 1, 2017

Enrollment Period

5.2 years

First QC Date

June 22, 2017

Last Update Submit

July 13, 2017

Conditions

Out-Of-Hospital Cardiac ArrestIn-hospital Cardiac Arrest

Keywords

UtsteinResuscitationEpidemiologyEmergency medicineResuscitation Registry

Outcome Measures

Primary Outcomes (2)

  • Incidence for OHCA and IHCA

    The aim of the RIAC study is to determine the number of cardiac arrest for out-of hospital cardiac arrest and for in-hospital cardiac arrest events.

    Latest data inclusion December, 31st 2019

  • Outcome for OHCA and IHCA

    The aim is to determine the percentage of Return of Spontaneous Circulation (ROSC) and six months survival with good neurological performance (assessed with Cerebral Performance Category scale) with a CPC score between 1-2, after 6 months of the cardiac arrest.

    Latest data inclusion March 31st, 2020

Secondary Outcomes (1)

  • 30 days survival

    Latest data inclusion December, 31st 2019

Study Arms (2)

Out-of-hospital cardiac arrest (OHCA)

An OHCA is defined as cessation of cardiac mechanical activity that occurs outside of the hospital setting and is confirmed by the absence of signs of circulation.

Other: Out-of-hospital cardiac arrest (OHCA)

In-hospital cardiac arrest (IHCA)

An IHCA is defined as cessation of cardiac mechanical activity that occurs inside of the hospital setting and is confirmed by the absence of signs of circulation.

Other: In-hospital cardiac arrest (IHCA)

Interventions

Out-of-hospital cardiac arrest (OHCA)OTHER

Data collection

Out-of-hospital cardiac arrest (OHCA)
In-hospital cardiac arrest (IHCA)OTHER

Data collection

In-hospital cardiac arrest (IHCA)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Cardiac arrest patients

You may qualify if:

  • All patients aged ≥ 18 years old who undergo an out-of-hospital cardiac or an in-hospital cardiac arrest.

You may not qualify if:

  • All patients without a cardiac arrest diagnosis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Italian Resuscitation Council

Bologna, 40128, Italy

RECRUITING

Related Links

MeSH Terms

Conditions

Out-of-Hospital Cardiac Arrest

Condition Hierarchy (Ancestors)

Heart ArrestHeart DiseasesCardiovascular Diseases

Study Officials

  • Erga Cerchiari, MD

    Department of Anesthesia and Intensive Care, Maggiore Hospital, AUSL, Bologna, Italy and Italian Resuscitation Council, Bologna, Italy

    PRINCIPAL INVESTIGATOR

  • Giuseppe Ristagno, MD, PhD

    IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Milan, Italy and Italian Resuscitation Council, Bologna, Italy

    STUDY DIRECTOR

  • Federico Semeraro, MD

    Department of Anesthesia and Intensive Care, Maggiore Hospital, AUSL, Bologna, Italy and Italian Resuscitation Council, Bologna, Italy

    STUDY DIRECTOR

  • Giovanni Gordini, MD

    Department of Anesthesia and Intensive Care, Maggiore Hospital, AUSL, Bologna, Italy and Italian Resuscitation Council, Bologna, Italy

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Federico Semeraro, MD

CONTACT

+39 333 6592670fsemeraro2008@gmail.com

Giuseppe Ristagno, PhD

CONTACT

+39 329 9738490gristag@gmail.com

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
6 Months
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 22, 2017

First Posted

July 18, 2017

Study Start

October 1, 2014

Primary Completion

December 30, 2019

Study Completion

December 30, 2019

Last Updated

July 18, 2017

Record last verified: 2017-07

Data Sharing

IPD Sharing
Will share

Data will be available for inclusion/participation in European cardiac arrest registries from European scientific societies or consortium, i.e. EuReCa registry from European Resuscitation Council. Data sets to be shared will be selected based on data required from the European registry. Data shared will be anonimized with no possibility to retrieve personal patient information. Data sharing will be approved by the RIAC Steering Committe and data will be transfered to the other Registry in a secure way under the direction of the Scientific Committee

Locations

IT(1)