Study on Patient Blood Management in Haematological Patients

NCT03217370 | Suspended

• 1 other identifier: S60580
• Study Type: interventional
• Target: 700
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators noticed a variable prescription of blood components to haematological patients in the hospital. This study will analyze the prescription and administration of blood components to Haematological patients (pre measurement). Based on these results guidelines on transfusion triggers will be updated and educated to the physicians and new ICT (information and communications technology) implementations will be added to the electronic order for blood components. The investigators hope to see afterwards (post measurement) a more stable prescription and administration of blood components and a more economic use of blood components.

Conditions

Blood Transfusion; Haematology

Keywords

patient blood management; restrictive transfusion

Outcome Measures

Primary Outcomes (1)

• how do haematologists prescribe blood components?

  The investigators use a questionaire (15-20 questions) to evaluate how haematologists prescribe red blood cells and platelets. Do they analyze the haemoglobin and platelet count before and after each blood transfusion? Do they apply single unit policy for RBC and platelet transfusions? Which triggers are used for RBC and platelet transfusion? Which guidelines are followed? The investigators will send this questionnaire to all haematologists (including haematologists in training) in 2017 (premeasurement) and in 2019-2020 (postmeasurement). The investigators will also use data (which is already available in the patient files) about blood transfusion to evaluate the ordering and administration of blood components during 1 year. For which indication is blood ordered? Is the Haemoglobin level known before the order is send to the blood bank?

  up to 1 year pre measurement and up to 1 year post measurement

Secondary Outcomes (1)

• what's the effect of the interventional phase?

  up to 1 year (post measurement)

Study Arms (1)

all haematologists

OTHER

There will be only one arm: the haematologists will all be included in the interventional phase. Interventions are: 1) rewriting guidelines to order blood components; 2) to show the last hemoglobin value on the orders for erytrocytes and the last platelet count on the orders dor thrombocytes and 3)implementation of a clinical decision support system in the electronic rodering of blood components to stimulate restrictive blood transfusion.

Other: education of guidelines

Interventions

education of guidelines OTHER

* Guidelines will be updated and education will be given to haematologists in several ways. * ICT implementations: a) last result of haemoglobin and platelet count will be shown on the electronic blood order; b) an electronical clinical decision support system will be implemented to order blood components

Also known as: ICT implementations in the electronic patient file

all haematologists

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• all adult patients hospitalised at the haematology wards of the University Hospitals of Leuven (UZ Leuven) between 01/08/2017 and 31/07/2018 (pre measurement) and between between 01/08/2019 and 31/07/2020 (post measurement)

You may not qualify if:

• ambulatory patients
• patients without blood transfusion administered in their hospitalised period
• patients with no haematological illness that were hospitalised at the haematological wards

Sponsors & Collaborators

• Universitaire Ziekenhuizen KU Leuven: lead

Study Sites (1)

University Hospitals Leuven

Leuven, 3000, Belgium

Location

Study Officials

• Els Costermans, MD

  advanced clinical nurse specialist

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: observational cross-sectional study with pre and post measurement and in between an interventional phase with education, IT implementations etc.

Study Record Dates

• First Submitted: July 5, 2017
• First Posted: July 14, 2017
• Study Start: August 1, 2017
• Primary Completion: September 30, 2021
• Study Completion: September 30, 2021
• Last Updated: February 18, 2019

Record last verified: 2019-02

Data Sharing

• IPD Sharing: Will not share

Locations

BE (1)