Transfusion Medicine - Prevention of Bedside Errors

NCT00127556 | Completed

• 1 other identifier: TM-PROBE study
• Study Type: interventional
• Target: 300
• Locations: 6 countries
• Sites: 12

Brief Summary

This study concerns the safety of blood transfusion. Prior to transfusion, staff should perform a number of essential safety checks to ensure that the correct patient is receiving the correct blood product. Evidence suggests that these safety checks are not always done. This study has been designed to assess the effect of a simple intervention on the performance of the bedside safety check. The hypothesis is that a simple intervention will improve the performance of the bedside check.

Conditions

Blood Transfusion

Keywords

Transfusion; Safety

Outcome Measures

Primary Outcomes (3)

• The primary endpoint is one proportion combining the 3 elements of the bedside check, that is: the proportion of transfusions in which the staff ask the patient to state his/her surname and first name and check that they are the same on the wristband

• the proportion of transfusions in which the staff check to see that the patient's surname, first name and hospital number are the same on the wristband and on the label attached to the unit by the blood bank

• the proportion of transfusions in which the staff check to see that the unit number is the same on the blood bag and on the label attached to the unit by the blood bank.

Interventions

Label applied to blood bag PROCEDURE

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Crossmatched red cells

You may not qualify if:

• Uncrossmatched red cells, platelets, fresh frozen plasma

Sponsors & Collaborators

• Dartmouth-Hitchcock Medical Center: lead
• BEST research collaborative: collaborator

Study Sites (12)

LA County and USC Medical Centre

Los Angeles, California, 90033, United States

Location

Massachusetts General Hospital

Boston, Massachusetts, 02114-2696, United States

Location

Beth Israel Deaconess Medical Centre

Boston, Massachusetts, 02215, United States

Location

Dartmouth-Hitchcock Medical Centre

Lebanon, New Hampshire, 03756, United States

Location

Cincinnati Children's Hospital Medical Centre

Cincinnati, Ohio, 45267, United States

Location

University Hospitals of Cleveland

Cleveland, Ohio, 44106, United States

Location

Royal North Shore Hospital

St Leonards, New South Wales, 2065, Australia

Location

Hospital Sirio Libanes Blood Bank

São Paulo, 01308-050, Brazil

Location

Hamilton Health Sciences

Hamilton, Ontario, L8N 3Z5, Canada

Location

Sunnybrook & Women's Hospital

Toronto, Ontario, M4N 3M5, Canada

Location

Haukeland University Hospital

Bergen, N-5021, Norway

Location

Great Ormond Street

London, United Kingdom

Location

Related Publications (1)

• Murphy MF, Casbard AC, Ballard S, Shulman IA, Heddle N, Aubuchon JP, Wendel S, Thomson A, Hervig T, Downes K, Carey PM, Dzik WH; BEST Research Collaborative. Prevention of bedside errors in transfusion medicine (PROBE-TM) study: a cluster-randomized, matched-paired clinical areas trial of a simple intervention to reduce errors in the pretransfusion bedside check. Transfusion. 2007 May;47(5):771-80. doi: 10.1111/j.1537-2995.2007.01189.x.

  PMID: 17465940 BACKGROUND

Related Links

• BEST collaboration

Study Officials

• Walter Dzik, MD

  Massachusetts General Hospital, USA

  PRINCIPAL INVESTIGATOR

• Mike F Murphy, FRCPath, MD

  National Blood Service, England

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Intervention Model: FACTORIAL
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: August 4, 2005
• First Posted: August 8, 2005
• Study Start: April 1, 2005
• Study Completion: December 1, 2005
• Last Updated: May 9, 2008

Record last verified: 2008-05

Locations

AU (1); GB (1); NO (1); BR (1); US (6); CA (2)