Study Stopped
No ZIKA cases at study site
ZIKAlliance Natural History Study
ZIKAllianceNH
Longitudinal Clinical and Virological Study Among Symptomatic Patients With Zika Virus Infection in the City of Sao Paulo, Brazil
1 other identifier
observational
N/A
1 country
1
Brief Summary
Study to enroll up to 1000 adult patients (\>18 years) presenting with febrile or rash illness of short duration (\<72h) in designated clinics in the State of Sao Paulo, Brazil.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
Started Apr 2018
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
June 29, 2017
CompletedFirst Posted
Study publicly available on registry
July 2, 2017
CompletedStudy Start
First participant enrolled
April 1, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 30, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
September 30, 2021
CompletedMay 18, 2022
May 1, 2022
3.5 years
June 29, 2017
May 17, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (3)
ZIKA Virus Infection
Clinical Characterization
up to one year
DENGUE Virus Infection
Clinical Characterization
up to one year
Chikungunya Virus Infection
Clinical Characterization
up to one year
Study Arms (1)
Symptomatic adults
adult patients (\>18 years) presenting with febrile or rash illness of short duration (\<72h)
Eligibility Criteria
General Population
You may qualify if:
- Rash or Fever illness
- within 72 hours of symptom onset
You may not qualify if:
- presence of symptoms or complications indicative of a bacterial infection
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University of Heidelberg Medical Centerlead
- University of Sao Paulocollaborator
Study Sites (1)
University of Sao Paulo
São Paulo, Brazil
Related Publications (1)
Avelino-Silva VI, Mayaud P, Tami A, Miranda MC, Rosenberger KD, Alexander N, Nacul L, Segurado A, Pohl M, Bethencourt S, Villar LA, Viana IFT, Rabello R, Soria C, Salgado SP, Gotuzzo E, Guzman MG, Martinez PA, Lopez-Gatell H, Hegewisch-Taylor J, Borja-Aburto VH, Gonzalez C, Netto EM, Saba Villarroel PM, Hoen B, Brasil P, Marques ETA, Rockx B, Koopmans M, de Lamballerie X, Jaenisch T; ZIKAlliance Clinical Study Group. Study protocol for the multicentre cohorts of Zika virus infection in pregnant women, infants, and acute clinical cases in Latin America and the Caribbean: the ZIKAlliance consortium. BMC Infect Dis. 2019 Dec 26;19(1):1081. doi: 10.1186/s12879-019-4685-9.
PMID: 31878895DERIVED
Biospecimen
blood, saliva, urine and genital fluid samples
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Thomas Jänisch
University Hospital Heidelberg
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Senior Scientist
Study Record Dates
First Submitted
June 29, 2017
First Posted
July 2, 2017
Study Start
April 1, 2018
Primary Completion
September 30, 2021
Study Completion
September 30, 2021
Last Updated
May 18, 2022
Record last verified: 2022-05
Data Sharing
- IPD Sharing
- Will not share