Key Insights

Highlights

Success Rate

89% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

9.1%

2 terminated out of 22 trials

Success Rate

88.9%

+2.4% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

31%

5 of 16 completed with results

Key Signals

5 with results89% success

Data Visualizations

Phase Distribution

14Total
Not Applicable (5)
P 1 (8)
P 2 (1)

Trial Status

Completed16
Unknown2
Terminated2
Withdrawn1
Recruiting1

Trial Success Rate

88.9%

Benchmark: 86.5%

Based on 16 completed trials

Clinical Trials (22)

Showing 20 of 20 trials
NCT06334393Phase 1Completed

Phase 1 Trial to Assess the Safety and Immunogenicity of an Inactivated, Adjuvanted Whole Zika Virus Vaccine Candidate (VLA1601) in Healthy Adults

NCT07358910Recruiting

Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective

NCT02952833Phase 1CompletedPrimary

ZIKA Vaccine in Naive Subjects

NCT02963909Phase 1CompletedPrimary

A Phase 1, First-in-human, Double-blinded, Randomized, Placebo-controlled Trial of a Zika Virus Purified Inactivated Vaccine (ZPIV) With Alum Adjuvant in Healthy Flavivirus-naive and Flavivirus-Primed Subjects.

NCT03624946Phase 1CompletedPrimary

Study in Healthy Volunteers Evaluating Safety and Pharmacokinetics of Zika Virus Immune Globulin (ZIKV-IG)

NCT03110770Phase 2Completed

VRC 705: A Zika Virus DNA Vaccine in Healthy Adults and Adolescents

NCT05041439Not ApplicableCompletedPrimary

Adherence to Care for Children With Congenital Zika Virus Infection in Puerto Rico

NCT03008122Phase 1CompletedPrimary

Phase I, Randomized, Double-blinded, Placebo-Controlled Dose De-escalation Study to Evaluate Safety and Immunogenicity of Alum Adjuvanted Zika Virus Purified Inactivated Vaccine (ZPIV) in Adults in a Flavivirus Endemic Area

NCT05589012UnknownPrimary

Evaluation of Viral Replication by Tonate Virus (TONV) and Zika Virus (ZIKV), Within an ex Vivo Trophoblast and Placental Model

NCT03204409Withdrawn

ZIKAlliance Natural History Study

NCT03631719Completed

Impact of Wolbachia Deployment on Arboviral Disease Incidence in Medellin and Bello, Colombia

NCT03161444Not ApplicableTerminated

Estimated Cumulative Incidence of Zika Infection at the End of the First Epidemic in the French West Indies in a Sample of Patients Followed for HIV Infection.

NCT04033068Phase 1CompletedPrimary

Safety and Immunogenicity of a Novel Vaccine Formulation MV-ZIKA-RSP (V187-001)

NCT04697147Not ApplicableCompletedPrimary

Zika and Neurodevelopment Among Infants in Grenada

NCT04478656Phase 1CompletedPrimary

Safety and Immunogenicity of BBV121

NCT03055585Not ApplicableTerminated

Applying Wolbachia to Eliminate Dengue

NCT03206541Completed

Neurologic Manifestations of the Arbovirus Infection in Colombia

NCT03425149Phase 1Completed

Randomized, Placebo-controlled, Observer-blinded Phase 1 Safety and Immunogenicity Study of Inactivated Zika Virus Vaccine Candidate in Healthy Adults

NCT03330600Not ApplicableCompletedPrimary

Efficacy of Aquatic Physiotherapy in Children With Microcephaly by Zika Virus Congenital Syndrome

NCT03776903CompletedPrimary

Evaluation of the Clinical Performance of the ZIKV Detect™ 2.0 IgM Capture ELISA

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