NCT03197727

Brief Summary

This study compares the associated risk factors between adults with tooth wear and age- and sex-matched controls without tooth wear.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Nov 2014

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 28, 2014

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2015

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 18, 2016

Completed
1.4 years until next milestone

First Submitted

Initial submission to the registry

June 22, 2017

Completed
1 day until next milestone

First Posted

Study publicly available on registry

June 23, 2017

Completed
Last Updated

June 23, 2017

Status Verified

June 1, 2017

Enrollment Period

7 months

First QC Date

June 22, 2017

Last Update Submit

June 22, 2017

Conditions

Tooth Wear

Keywords

Tooth wear, risk factors, saliva, diet, oral hygiene

Outcome Measures

Primary Outcomes (1)

  • Saliva test

    Highly acidic saliva will be in the red section, pH 5.0 - 5.8. Moderately acidic saliva will be found in the yellow section, pH 6.0 - 6.6. Healthy saliva will be in the green section pH 6.8 - 7.8.

    1 day

Secondary Outcomes (1)

  • Tooth wear

    1 day

Study Arms (1)

GC Saliva-Check BUFFER

OTHER

Saliva test pH Buffering capacity Flow rate

Diagnostic Test: GC Saliva-Check BUFFER

Interventions

GC Saliva-Check BUFFERDIAGNOSTIC_TEST

Evaluating the saliva flow rate, saliva pH and saliva buffering capacity

GC Saliva-Check BUFFER

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Subject is in good health. Subject is able to understand and read the questionnaire.

You may not qualify if:

  • Wearing orthodontic appliances, Having crowns or partial dentures Using any medications.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (3)

  • Fung A, Brearley Messer L. Tooth wear and associated risk factors in a sample of Australian primary school children. Aust Dent J. 2013 Jun;58(2):235-45. doi: 10.1111/adj.12055. Epub 2013 May 5.

    PMID: 23713646BACKGROUND

  • El Aidi H, Bronkhorst EM, Huysmans MC, Truin GJ. Multifactorial analysis of factors associated with the incidence and progression of erosive tooth wear. Caries Res. 2011;45(3):303-12. doi: 10.1159/000328671. Epub 2011 Jun 8.

    PMID: 21654171BACKGROUND

  • Zero DT, Lussi A. Erosion--chemical and biological factors of importance to the dental practitioner. Int Dent J. 2005;55(4 Suppl 1):285-90. doi: 10.1111/j.1875-595x.2005.tb00066.x.

    PMID: 16167607BACKGROUND

MeSH Terms

Conditions

Tooth Wear

Condition Hierarchy (Ancestors)

Tooth DiseasesStomatognathic Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Postdoc reseacher, DDS, Ph.D

Study Record Dates

First Submitted

June 22, 2017

First Posted

June 23, 2017

Study Start

November 28, 2014

Primary Completion

June 30, 2015

Study Completion

January 18, 2016

Last Updated

June 23, 2017

Record last verified: 2017-06

Data Sharing

IPD Sharing
Will not share