NCT03189108|Terminated
Study Stopped
PI left NIH
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PI left NIH
Sponsor study identifier
Secondary identifiers
observational
22
1 country
1
Study Start
May 22, 2017
Actual (reported)Primary Completion
May 18, 2023
Actual (reported)Study Completion
May 18, 2023
Actual (reported)Background: Researchers want to study fluids and blood of people with cancer. The fluids are from the abdomen and around the lungs. Studying these might help researchers learn about the biology of cancer. This may lead to better ways to treat cancer. Objectives: To study the biology of cancer. Eligibility: Adults 18 and older with malignant solid tumors. Design: Participants will be screened with medical history, blood tests, and confirmation of diagnosis. Participants will have samples taken at regularly scheduled procedures. Fluids from the abdomen and/or lungs will be taken as part of the procedures. Blood will be taken separately. Participants may be asked to give more samples at future procedures.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
May 18, 2023
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
May 22, 2017
Actual (reported)June 15, 2017
Actual (reported)June 16, 2017
Actual (reported)May 18, 2023
Actual (reported)May 18, 2023
Actual (reported)To obtain blood samples, ascites and pleural effusion samples from patients with solid tumor malignancies, with the intent of performing translational studies related to cancer.
Experimental - Translational study outcomes from the collection/analysis of blood samples; and ascites and pleural effusion samples from patients with solid tumor malignancies.
Ongoing
Develop the malignant fluid as a culture model to replicate intraperitoneal growth of ovarian cancers.
ongoing
Characterize malignant effusion composition through immunohistochemistry and flow cytometry.
ongoing
Patients with a diagnosis of malignant solid tumor
Patients who are being seen in follow up, consultation, or presenting for enrollment on a clinical trial at the NIH Clinical Center
National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States
Kevin C Conlon, M.D.
National Cancer Institute (NCI)
22 participants (actual enrollment reported by the registry).
First Submitted
June 15, 2017
First Posted
June 16, 2017
Study Start
May 22, 2017
Actual (reported)Compare immune cell phenotype in ascites and blood from the patient.
ongoing
Study in vivo characteristics of matched tumor cells and peripheral blood leukocytes from the same patient in xenograft models
ongoing
Establish a bank of clinically annotated samples for translational science.
ongoing
Contact the study team to confirm eligibility.
Primary Completion
May 18, 2023
Actual (reported)Study Completion
May 18, 2023
Actual (reported)Last Updated
January 2, 2026
Record last verified: 2025-12
All IPD recorded in the medical record will be shared with intramural investigators upon request.
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Source: ClinicalTrials.gov.
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