Stroke Cincinnati Prehospital Stroke Severity Scale Evaluation iN prEhospital
SCENE
Evaluation of the Performances of the Cincinnati Prehospital Stroke Severity Scale Realized During Telephone Call With Emergency Department Physicians to Predict Large-vessel Occlusion
1 other identifier
observational
1,272
1 country
12
Brief Summary
The effectiveness of acute ischemic stroke (AIS) management has improved considerably in recent years with thrombolysis and more recently with mechanical thrombectomy (MT). Currently, mechanical thrombectomy can only be performed in stroke unit with an interventional neuroradiology center by experienced/qualified interventional neuroradiologists. In the Rhone area, only one hospital has the authorization to perform mechanical thrombectomy. Therefore, transferring directly eligible acute ischemic stroke patients for mechanical thrombectomy to this center constitutes an important stake of the triage of suspected acute ischemic stroke patients. Some validated scores for the identification of severe strokes and large vessel occlusion, including the Cincinnati prehospital stroke severity scale (CPSSS), appear to be relevant for pre-hospital use in order to identify patients potentially eligible for mechanical thrombectomy and address them to a stoke unit with interventional radiology center.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jun 2018
Typical duration for all trials
12 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
June 7, 2017
CompletedFirst Posted
Study publicly available on registry
June 8, 2017
CompletedStudy Start
First participant enrolled
June 25, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 31, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
January 31, 2022
CompletedNovember 21, 2022
November 1, 2022
3.6 years
June 7, 2017
November 18, 2022
Conditions
Outcome Measures
Primary Outcomes (1)
Performances of Cincinnati prehospital stroke severity scale
The Cincinnati prehospital stroke severity scale is composed of 3 items: 2 points if the patient has a deviation of the gaze, 1 point if the patient is not able to give the date and answer to a simple order such as closing the eyes or clenching the fist and 1 point if the patient presents a hemiplegia. The CPSSS score ranges from 0 to 4, highest value indicating the worst score. It will be considered positive if it is equal to 2 or more. Performances will be evaluated in terms of sensitivity, specificity, positive and negative predictive values.
1 day
Study Arms (1)
Patients with suspected ischemic stroke
The cohort will be constituted of patients treated for a stroke suspicion after calling emergency medical services of the Rhone and presenting a symptom-onset (the last time the patient was seen without deficit) less than 6 hours.
Interventions
Tests from Cincinnati prehospital stroke severity scale (CPSSS) will be carried out by the physician at emergency medical services on telephone call with firemen, paramedics or the emergency medical services team for any stroke suspicion that meets the criteria for inclusion. Emergency department physician will have to follow a standardized questionnaire to complete the different items of the score. The score will not be calculated by emergency department physician and will not influence the orientation and management of patients. The final diagnosis will be the presence or absence of a large vessel occlusion. This diagnosis will be done on cerebral imaging by a neurologist.
Eligibility Criteria
Patients with stroke of the Rhone area after emergency medical services call
You may qualify if:
- Consecutive patients calling emergency medical services for suspected acute ischemic stroke
You may not qualify if:
- Symptom onset (or the last time the patient was seen without deficit ) of more than 6 hours
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (12)
Neurologie, Hôpital Neurologique - HCL
Bron, France
SAMU 69 , Hôpital Edouard Herriot
Lyon, 69003, France
Médecine d'urgence, Clinique de la Sauvegarde
Lyon, France
Médecine d'urgence, Hôpital de la Croix-Rousse - HCL
Lyon, France
Médecine d'urgence, Hôpital Desgenettes
Lyon, France
Médecine d'urgence, Hôpital Mutualiste Médipôle
Lyon, France
Médecine d'urgence, Hôpital Saint Joseph Saint Luc
Lyon, France
Urgentiste, Centre Hospitalier Lyon Sud
Pierre-Bénite, France
Médecine d'urgence, CH de Roanne
Roanne, France
Médecine d'urgence, Hôpital Nord-Ouest
Tarare, France
Services Médecine d'urgence et Neurologie, CH de Vienne
Vienne, France
Services Neurologie et Médecine d'urgence, CH de Villefranche sur Saône
Villefranche-sur-Saône, France
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
June 7, 2017
First Posted
June 8, 2017
Study Start
June 25, 2018
Primary Completion
January 31, 2022
Study Completion
January 31, 2022
Last Updated
November 21, 2022
Record last verified: 2022-11
Data Sharing
- IPD Sharing
- Will not share