Motor Imagery Ability After Stroke

NCT03661073 | Completed

• 1 other identifier: 69HCL18_0059
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

Individuals with stroke may experience sensory-motor deficit and/or neglect, with possible reduction in motor imagery ability (MI). To our knowledge, no study completely investigated MI ability in one individual whereas MI practice can be performed using visual or kinesthetic modalities (respectively visualizing with mind's eyes or imagining movement using sensation) and internal or external perspectives (performing action as spectator or as actor). This study aims to investigate MI ability in patients with stroke as compared to aged-matched healthy individuals. The investigators will assess explicit MI ability using 3 questionnaires (Movement Imagery Questionnaire-RS - MIQ-RS, Kinesthetic and Visual Imagery Questionnaire-20 - KVIQ-20, Vividness of Movement Imagery Questionnaire-2 - VMIQ-2) and 2 tests (imagined Time Up and Go - iTUG, imagined Box and Block test - iBBT). Outcome parameters will be i) the composite score of vividness measured for all tests using Likert scales, ii) the temporal equivalence between MI and Physical practice (PP - where MI/PP ratio equal to 1 indicate good MI ability and respect of temporal equivalence between MI and PP) and iii) the amplitude of electrodermal activity. The investigators will also study implicit MI ability using a hand laterality judgment task. Outcomes parameters will be response time (i.e. the duration to identify the hand laterality) and the percentage of correct responses.

Conditions

Stroke

Outcome Measures

Primary Outcomes (1)

• Score of vividness

  Participants will self-report vividness that describe the success in imagining movements using a 5-points Likert scale (1=no image or no sensation to 5=image as clear as PP or sensation as intense as PP) for the KVIQ-20. The investigators will average the vividness for each items of the questionnaire.

  Day 1

Secondary Outcomes (15)

• Temporal equivalence measured during KVIQ-20

  Day 1

• Amplitude of electrodermal responses that will be measured during imagined movement with reference to actual movements measured during KVIQ-20.

  Day 1

• Score of vividness measured during VMIQ -2

  Day 1

• Amplitude of electrodermal responses that will be measured during imagined movement with reference to actual movements measured during VMIQ -2.

  Day 1

• Score of vividness measured during MIQ-RS.

  Day 3

Study Arms (2)

Stroke

EXPERIMENTAL

The investigator will include patients with stroke (either hemorrhagic or ischemic) with or without neglect in the experimental group.

Behavioral: Assessment of motor imagery ability

Healthy subjects

SHAM COMPARATOR

The investigator will include healthy subjects aged-matched to participants of the experimental group in the control group.

Behavioral: Assessment of motor imagery ability of healthy subject

Interventions

Assessment of motor imagery ability BEHAVIORAL

The intervention will last 3 hours ± 45 minutes, the assessment will be spread over 3 sessions of 1 hour ± 15 minutes on one week. The time between two sessions will depend on patient fatigability and availability. The VMIQ-2 and the KVIQ-20 will be realized during the first session. In the second session, patients will perform the hand laterality judgment task and the MIQ-RS. During the last session the Timed up and go and the box and block test will be realized.

Stroke

Assessment of motor imagery ability of healthy subject BEHAVIORAL

The intervention will last 2 hours ± 15 minutes. All the tests will be spread over 1 session. Assessment order will be VMIQ-2, KVIQ-20, the hand laterality judgment task, the after a break MIQ-RS, iTUG and iBBT.

Healthy subjects

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• For both groups:
• be more than 18 years old
• be less than 75 years old
• benefit from social security
• For experimental group:
• patient admitted in Henry Gabrielle hospital for rehabilitation
• patient with one single episode of stroke

You may not qualify if:

• For patients:
• sign of cognitive decline (MMSE score under 27/30)
• evolutionary pathology associated
• For healthy subjects:
• \- neurological or orthopaedical history

Sponsors & Collaborators

• Hospices Civils de Lyon: lead

Study Sites (1)

Hôpital Henry Gabrielle

Saint-Genis-Laval, 69230, France

Location

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 1, 2018
• First Posted: September 7, 2018
• Study Start: July 17, 2018
• Primary Completion: January 17, 2022
• Study Completion: January 17, 2022
• Last Updated: March 14, 2023

Record last verified: 2023-03

Locations

FR (1)