The Surgical Treatment of Total Brachial Plexus Avulsion Injury-A Retrospective Study of 73 Patients

NCT03162393 | Completed

• 1 other identifier: NSFC-H0605/81501871
• Study Type: observational
• Target: 73
• Locations: 0 countries
• Sites: N/A

Brief Summary

Brachial plexus avulsion injury (BPAI) caused by traction injury, especially total root avulsion, represents a severe handicap for the patient. Despite recent progress in diagnosis and microsurgical repair, the prognosis in such cases remains unfavorable. We need to find an relatively optimal surgical treatment.

Conditions

Brachial Plexus Injury

Keywords

brachial plexus; avulsion injury

Outcome Measures

Primary Outcomes (1)

• physical examination

  the motor and sensory function recovery of the recipient nerves

  at least 3 years post-operative

Study Arms (6)

group 1

phrenic nerve transfer to musculocutaneous nerve; spinal accessory transfer to suprascapular nerve; intercostal nerve transfer to triceps branch, radial nerve and axillary nerve; contralateral C7 nerve transfer to median nerve

Procedure: nerve transfer

group 2

phrenic nerve transfer to musculocutaneous nerve; spinal accessory transfer to suprascapular nerve; intercostal nerve transfer to triceps branch and radial nerve; contralateral C7 nerve transfer to median nerve

Procedure: nerve transfer

group 3

spinal accessory transfer to suprascapular nerve; intercostal nerve transfer to triceps branch, radial nerve and axillary nerve; contralateral C7 nerve transfer to median nerve and musculocutaneous nerve

Procedure: nerve transfer

group 4

spinal accessory transfer to suprascapular nerve; intercostal nerve transfer to triceps branch and radial nerve; contralateral C7 nerve transfer to median nerve and musculocutaneous nerve

Procedure: nerve transfer

group 5

spinal accessory transfer to suprascapular nerve; intercostal nerve transfer to musculocutaneous nerve, radial nerve and axillary nerve; contralateral C7 nerve transfer to median nerve and triceps branch

Procedure: nerve transfer

group 6

spinal accessory transfer to suprascapular nerve; intercostal nerve transfer to musculocutaneous nerve and radial nerve; contralateral C7 nerve transfer to median nerve and triceps branch

Procedure: nerve transfer

Interventions

nerve transfer PROCEDURE

group 1; group 2; group 3; group 4; group 5; group 6

Eligibility Criteria

• Age: 12 Years - 60 Years
• Sex: all
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Between 1999 and 2006, a total of approximately 200 patients with posttraumatic total BPAI underwent surgical exploration and reconstruction of the brachial plexus and 109 agreed to participate in our study. Seventy-three patients were enrolled and 36 were excluded.

You may qualify if:

• global root avulsion brachial plexus injury, a minimum postoperative interval of 3 years, all operations performed by the same medical team, nerve transfer was the only reconstruction method.

You may not qualify if:

• diabetes, Volkmann contracture, fracture on the affected limb, rib fracture, brain trauma.

Sponsors & Collaborators

• Huashan Hospital: lead

MeSH Terms

Conditions

Fractures, Avulsion

Interventions

Nerve Transfer

Condition Hierarchy (Ancestors)

Fractures, Bone; Wounds and Injuries

Intervention Hierarchy (Ancestors)

Neurosurgical Procedures; Surgical Procedures, Operative

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Doctor

Study Record Dates

• First Submitted: May 19, 2017
• First Posted: May 22, 2017
• Study Start: January 1, 2016
• Primary Completion: December 31, 2016
• Study Completion: December 31, 2016
• Last Updated: May 22, 2017

Record last verified: 2017-05