Perfusion and Collaterals Imaging With C-arm CT
Perfusion and Collateral Imaging Using C-arm Computed Tomography in the Neuro-Angiography Suite
1 other identifier
observational
30
1 country
1
Brief Summary
Single-center, single-arm pilot study to evaluate the ability of C-arm computed tomography imaging to assess perfusion parameters, collateral vessels, recanalization and brain ischemia in patients with suspected or proven ischemic stroke or brain ischemia in the neuro-angiography suite.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started May 2017
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 11, 2017
CompletedFirst Submitted
Initial submission to the registry
May 18, 2017
CompletedFirst Posted
Study publicly available on registry
May 22, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2019
CompletedOctober 16, 2018
October 1, 2018
1.9 years
May 18, 2017
October 15, 2018
Conditions
Outcome Measures
Primary Outcomes (1)
Number of participants with clinically valuable CACT perfusion images based on a 5-point Likert scale
C-arm computed tomography acquisition perfusion/collateral protocols that provide sufficient image quality to be able to assess ischemic brain perfusion, recanalization and ischemic regions effectively. A 5-point Likert scale questionnaire will be used to evaluate image quality. Cerebral blood volume measurements will also be calculated by image processing software.
1 year
Secondary Outcomes (1)
Number of participants with CACT perfusion images of comparable quality to standard imaging modalities based on a 5-point Likert scale
1 year
Study Arms (1)
Ischemic Stroke
Percutaneous neurovascular treatment of acute ischemic stroke patients.
Interventions
An additional C-arm CT imaging scan will be done during neurovascular treatment to evaluate perfusion and collateral vessels in ischemic stroke patients.
Eligibility Criteria
Patients with suspected or proven ischemic stroke or brain ischemia who require diagnostic and/or interventional imaging in the neuro-angiography suite.
You may qualify if:
- Subject has suspected or proven ischemic stroke or brain ischemia.
- Subject requires diagnostic and/or interventional imaging in the neuro-angiography suite.
- Subject or subject's legally authorized representative has signed an institutionally approved research informed consent form.
- Subject ≥ 18 years old.
You may not qualify if:
- Subject or subject's legally authorized representative is unable or unwilling to consent to the study.
- Subject with documented contrast medium injection contraindication due to severe kidney disease or allergy.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University Health Network, Torontolead
- Philips Healthcarecollaborator
Study Sites (1)
Toronto Western Hospital - University Health Network
Toronto, Ontario, M5T 2S8, Canada
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Vitor Pereira, MD
University Health Network - Toronto Western Hospital
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor of Radiology and Surgery
Study Record Dates
First Submitted
May 18, 2017
First Posted
May 22, 2017
Study Start
May 11, 2017
Primary Completion
April 1, 2019
Study Completion
April 1, 2019
Last Updated
October 16, 2018
Record last verified: 2018-10
Data Sharing
- IPD Sharing
- Will not share