Effects of Whole-Body Vibration Training Versus Balance Training in Patients With Severe Chronic Obstructive Pulmonary Disease

NCT03157986 | Completed

• 1 other identifier: WBVT Balance Study
• Study Type: interventional
• Target: 48
• Locations: 1 country
• Sites: 1

Brief Summary

Aim of this study is to compare the effects of whole-body Vibration Training versus conventional Balance Training on Balance performance, gait quality and exercise capacity in patients with severe chronic obstructive pulmonary disease. Patients will be recruited during a 3-week inpatient pulmonary rehabilitation program and will be randomized into one of two intervention groups. On top of a standardized endurance and strength Training program (5 days per week) patients in both groups will perform an additional Balance Training (on 3 days per week). Patients in both Groups will perform the same 4 different Balance exercises (2x1 Minute each): dynamic squats with closed eyes, heel raise, semi-Tandem stance and single leg stance but on a different surface. The Vibration Training Group will perform the exercises on a side-alternating Vibration platform (Galileo) at frequencies between 15 to 26 Hertz and the control Group will perform exercises on instable objects like Balance pads. The degree of difficulty in both Groups will be individually adjusted and will be progressively increased, if possible.

Conditions

Chronic Obstructive Pulmonary Disease

Keywords

COPD; Balance; Whole Body Vibration Training; pulmonary rehabilitation; exercise

Outcome Measures

Primary Outcomes (1)

• Change in Balance Performance during semi Tandem stance

  patients stand still for 10 seconds with closed eyes on a force platform that measures absolute path length of the center of force.

  measurement on Day 1 and 21

Secondary Outcomes (11)

• Change in muscle power during counter movement jump

  measurement on Day 1 and 21

• Change in performance of the 5-Repetition-Raise-Test

  measurement on Day 1 and 21

• Change in performance of the 1-Minute-Chair-Rise-Test

  measurement on Day 1 and 21

• Change in Peak muscle strength of the knee Extension muscles

  measurement on Day 1 and 21

• Change in Peak muscle strength of the knee Flexion muscles

  measurement on Day 1 and 21

Study Arms (2)

Whole Body Vibration training

ACTIVE COMPARATOR

Balance Training on a Vibration platform

Other: Balance Training on a vibration platform

Conventional Balance training

ACTIVE COMPARATOR

Balance Training on a Balance board

Other: Conventional Balance training

Interventions

Balance Training on a vibration platform OTHER

n=24 patients with severe chronic obstructive pulmonary disease. Exercises will be performed on a side-alternating Vibration platform (Galileo) at frequencies between 15 to 26 Hertz.

Whole Body Vibration training

Conventional Balance training OTHER

n=24 patients with COPD, Exercises will be performed on a Balance pad

Conventional Balance training

Eligibility Criteria

• Age: 50 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• COPD stage III or IV according to the global initiative for chronic obstructive lung disease
• impaired exercise capacity (6 Minute walk distance of less than 70% of the reference value from Troosters et al.)

You may not qualify if:

• current acute exacerbation of COPD
• carbon dioxide pressure of more than 45 mmHg at rest
• any contraindication for vibration Training (e.g. acute deep vein thrombosis)

Sponsors & Collaborators

• Schön Klinik Berchtesgadener Land: lead

Study Sites (1)

Schön Klinik Berchtesgadener Land

Schönau am Königssee, Bavaria, 83471, Germany

Location

Related Publications (1)

• Gloeckl R, Schneeberger T, Leitl D, Reinold T, Nell C, Jarosch I, Kenn K, Koczulla AR. Whole-body vibration training versus conventional balance training in patients with severe COPD-a randomized, controlled trial. Respir Res. 2021 May 4;22(1):138. doi: 10.1186/s12931-021-01688-x.

  PMID: 33947416 DERIVED

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive; Motor Activity

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Behavior

Study Officials

• Klaus Kenn, MD

  Schoen Klinik Berchtesgadener Land

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Head physican (department of pneumology)

Study Record Dates

• First Submitted: May 16, 2017
• First Posted: May 17, 2017
• Study Start: May 15, 2017
• Primary Completion: August 16, 2019
• Study Completion: August 16, 2019
• Last Updated: December 24, 2019

Record last verified: 2019-12

Data Sharing

• IPD Sharing: Will share

Locations

DE (1)