Effects of Treadmill Versus Cycling Endurance Training in Patients With COPD

NCT03120169 | Completed

• 1 other identifier: treadmill vs. cycling in COPD
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Aim of this study is to investigate the effects of treadmill versus cycling endurance training on Balance, gait performance and exercise capacity in patients with severe chronic obstructive pulmonary disease. Patients will be recruited during a 3-week inpatient pulmonary rehabilitation program and will be randomized into one of two intervention groups. Walking intensity in the treadmill group will be set at 80 percent of the average speed of the 6-minute walking test. The cycling group will exercise at an intensity of 60 percent according to an Initial incremental cycling test. Patients will perform 5 to 6 training sessions per week. The total exercise duration will be progressively increased from 10 to 30 minutes. Walking or cycling intensity will also be progressively increased if perceived exertion during exercise is rated below 3 on the modified 10-point Borg scale.

Conditions

Chronic Obstructive Pulmonary Disease

Keywords

COPD; exercise; training; cycling; treadmill; walking; pulmonary rehabilitation

Outcome Measures

Primary Outcomes (1)

• Change in step symmetry during 20m walking

  Patients walk 20m while wearing the Mc Roberts move test device (triaxial accelerometer) which performs a gait analysis

  measurement on day 1 and 21

Secondary Outcomes (10)

• Change in balance performance during semi-tandem stance

  measurement on day 1 and 21

• Change in balance performance during Romberg stance

  measurement on day 1 and 21

• Change in balance performance during single leg stance

  measurement on day 1 and 21

• Change in muscle power during counter movement jump

  measurement on day 1 and 21

• Change in 1 Minute sit to stand test

  measurement on day 1 and 21

Study Arms (2)

treadmill endurance training

ACTIVE COMPARATOR

Other: treadmill endurance training

cycling endurance training

ACTIVE COMPARATOR

Other: cycling endurance training

Interventions

treadmill endurance training OTHER

n = 15 patients with COPD. Walking intensity will be initially set at 80 percent of 6-minute Walking test Speed with progressive increase in Duration and intensity.

treadmill endurance training

cycling endurance training OTHER

n=15 patients with COPD. Cycling intensity will initially be set at 60 percent of Peak work rate with progressive increase in Duration and intensity

cycling endurance training

Eligibility Criteria

• Age: 50 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• COPD Stage III or IV according to the global initiative for chronic obstructive lung disease
• impaired exercise capacity (6 Minute walk distance of less than 70% of the reference values from Troosters et al.)

You may not qualify if:

• acute, severe exacerbation of COPD
• carbon dioxide of more than 45 mmHg at rest
• any disabilities that prevent patient form walking or cycling
• Patient is not able to walk 20 meters without any aid (for example rollator)

Sponsors & Collaborators

• Schön Klinik Berchtesgadener Land: lead

Study Sites (1)

Schoen Klinik Berchtesgadener Land

Schönau am Königssee, 83471, Germany

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive; Motor Activity

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Behavior

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Head physican (department of pneumology)

Study Record Dates

• First Submitted: April 13, 2017
• First Posted: April 19, 2017
• Study Start: March 30, 2017
• Primary Completion: November 27, 2017
• Study Completion: November 27, 2017
• Last Updated: February 15, 2018

Record last verified: 2018-02

Locations

DE (1)