The Incidence, Effect and Persistence of Fragmented-QRS, in Patients Presenting With ST-Elevation Myocardial Infarction
1 other identifier
observational
64
1 country
1
Brief Summary
This study will assess the incidence, effect and persistence of F-QRS (Fragmented-QRS) in STEMI (ST-elevation Myocardial Infarction) patients post-PCI (percutaneous coronary intervention). The aim is to add to the existing research field surrounding F-QRS. It is hypothesised that patients with F-QRS present on the surface ECG, following PCI, will have incurred a higher degree of damage. As a result, it is hypothesised that these patients will have reduced LV (left-ventricular) systolic function, increased incidence of regional wall motion abnormalities (RWMAs), and increased troponin levels on admission. This study will additionally look for correlations between F-QRS and culprit vessels. To our knowledge there is minimal research regarding this.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Sep 2017
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
May 15, 2017
CompletedFirst Posted
Study publicly available on registry
May 17, 2017
CompletedStudy Start
First participant enrolled
September 1, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
May 30, 2018
CompletedJune 18, 2019
June 1, 2019
8 months
May 15, 2017
June 17, 2019
Conditions
Outcome Measures
Primary Outcomes (1)
F-QRS measurements
recorded from ECG
Over 6 months
Secondary Outcomes (2)
Left ventricular ejection fraction (LVEF)
Over 6 months
T-Troponin tests
Over 6 months
Study Arms (1)
STEMI patients treated with primary PCI
Database analysis only
Eligibility Criteria
100 STEMI patients treated with primary PCI.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
New Cross Hospital
Wolverhampton, West Midlands, WV10 0QP, United Kingdom
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Joseph Kelly
The Royal Wolverhampton NHS Trust
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER GOV
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
May 15, 2017
First Posted
May 17, 2017
Study Start
September 1, 2017
Primary Completion
May 1, 2018
Study Completion
May 30, 2018
Last Updated
June 18, 2019
Record last verified: 2019-06
Data Sharing
- IPD Sharing
- Will not share
No IPD will be available to other researchers