Correlation of QT Dispersion With Myocardial Perfusion in Patients With ST Elevation Myocardial Infarction Treated by Primary Per Cutaneous Coronary Intervention
1 other identifier
observational
235
1 country
1
Brief Summary
To correlate QT dispersion on 12-lead surface ECG with myocardial reperfusion evaluated by myocardial blush grade and Thrombolysis in myocardial infarction (TIMI) flow grades in patients with ST elevation myocardial infarction treated by Primary Per cutaneous coronary intervention
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jul 2018
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
August 27, 2017
CompletedFirst Posted
Study publicly available on registry
September 1, 2017
CompletedStudy Start
First participant enrolled
July 1, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 1, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2019
CompletedJuly 3, 2018
June 1, 2018
1 year
August 27, 2017
June 30, 2018
Conditions
Outcome Measures
Primary Outcomes (2)
Correlation of QT dispersion on 12-lead surface ECG with myocardial reperfusion
Use 12 lead ECG to calculate QT interval and QT dispersion comparing ECG before and after myocardial reperfusion.
1 year
Evaluation of myocardial perfusion by coronary angiography by assessing 2 parameters TIMI flow and myocardial blush grade
Use coronary angiography to detect myocardial blush grade and TIMI flow to assess myocardial reperfusion
1 year
Interventions
Primary Percutaneous coronary intervention
Eligibility Criteria
This cross sectional observational study will include patients with acute STEMI of different ages from cardiology department, Assiut University Hospital who will undergo primary percutaneous coronary intervention (PCI).
You may qualify if:
- Patients will be enrolled in this study if they fulfilled the criteria of acute ST elevation myocardial infarction eligible to be treated with primary Percutaneous coronary intervention
You may not qualify if:
- Non-ST elevation myocardial infarction, prior history of myocardial infarction or surgical revascularization,
- Electrolyte disturbance.
- history of medications that may affect QT (anti-arrhythmic, anti-psychotic, and anti-depressant drugs),
- patients with cardiogenic shock or needing IABP.
- patients with previous CABG.
- Patients with implantable devices and pacemakers.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Assiut university
Asyut, 71641, Egypt
Related Publications (1)
Karahan Z, Yaylak B, Ugurlu M, Kaya I, Ucaman B, Ozturk O. QRS duration: a novel marker of microvascular reperfusion as assessed by myocardial blush grade in ST elevation myocardial infarction patients undergoing a primary percutaneous intervention. Coron Artery Dis. 2015 Nov;26(7):583-6. doi: 10.1097/MCA.0000000000000285.
PMID: 26166018BACKGROUND
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Hatem Helmy
assistant professor
- STUDY CHAIR
Hosam Hasan
professor
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
August 27, 2017
First Posted
September 1, 2017
Study Start
July 1, 2018
Primary Completion
July 1, 2019
Study Completion
September 1, 2019
Last Updated
July 3, 2018
Record last verified: 2018-06