NCT03155152

Brief Summary

Different types of high-intensity interval training (HIIT) sessions are used by athletes in order to improve their physical performance, but innovative approaches to training are lacking. Therefore, in Part A of this study the physiological response to a standard HIIT and a new decremental exercise training (DECT) will be compared in runners and cyclists. Next, in Part B the training effects of a 4-week block of the HIIT and DECT will be compared.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
55

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jun 2017

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 12, 2017

Completed
4 days until next milestone

First Posted

Study publicly available on registry

May 16, 2017

Completed
16 days until next milestone

Study Start

First participant enrolled

June 1, 2017

Completed
2.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 11, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 11, 2019

Completed
Last Updated

March 18, 2020

Status Verified

February 1, 2019

Enrollment Period

2.5 years

First QC Date

May 12, 2017

Last Update Submit

March 17, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change in exercise performance

    Time taken to cover a fixed distance, in minutes

    measured before and after the 4-week training block, during a time-trial (40 km cycling or 10 km running)

Secondary Outcomes (2)

  • Change in maximal oxygen uptake

    Measured during a maximal incremental exercise test before and after the 4-week training block

  • Average oxygen uptake

    The two training session are performed within one week

Study Arms (2)

DECT Group

EXPERIMENTAL

The DECT session consists of four bouts of 4 min high-intensity "decremental" exercise with 3 min of active recovery between bouts. Load is progressively decreased throughout each exercise bout. The training period will last for a total of 4 weeks, with three weekly sessions of supervised training

Other: DECT

HIIT Group

ACTIVE COMPARATOR

The HIIT session consists of four bouts of 4 min high-intensity "decremental" exercise with 3 min of active recovery between bouts. Load is kept constant throughout each exercise bout. The training period will last for a total of 4 weeks, with three weekly sessions of supervised training

Other: HIIT

Interventions

DECTOTHER

The DECT program consists of a 4-week training intervention with three weekly sessions of high-intensity interval training, in which during each exercise bout the workload is imposed in a decremental fashion.

DECT Group
HIITOTHER

The HIIT program consists of a 4-week training intervention with three weekly sessions of high-intensity interval training, in which during each exercise bout the workload is kept constant.

HIIT Group

Eligibility Criteria

Age18 Years - 40 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Age: 18-40 years
  • Healthy, i.e. normal physical and mental status (not taking any medication on a regular basis for more than a month, except contraceptive medication)
  • Normal Body-Mass-Index (BMI): 18.5-24.9 kg·m-2
  • Well-trained athletes: V̇O2max \> 55.1 ml·min-1·kg-1 for men and \> 50.1 ml·min-1·kg-1 for women
  • Normal lung function
  • Non-smoking
  • Willing to adhere to the general study rules

You may not qualify if:

  • Women who are pregnant or breast feeding
  • Intention to become pregnant during the course of the study
  • Known or suspected non-compliance, drug or alcohol abuse
  • Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participant
  • Previous enrolment into the same part (A or B) of the current study
  • Enrolment of the investigator, his/her family members, employees and other dependent persons
  • Acute or chronic illness
  • Intake of medications affecting performance or the respiratory, cardiovascular or neuromuscular system
  • Insufficient training history (\<3 yrs of participation in competitive cycling/running) or training volume (\<40 km running/week or 150 km cycling/week) in the previous 6 months
  • Recent (\<3 months) history of orthopaedic injury or participation in structured high-intensity training blocks

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Exercise Physiology Lab, Institute of Human Movement Sciences and Sport, ETH Zurich

Zurich, Canton of Zurich, 8057, Switzerland

Location

Study Officials

  • Christina M Spengler, Prof.

    ETH Zurich

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 12, 2017

First Posted

May 16, 2017

Study Start

June 1, 2017

Primary Completion

December 11, 2019

Study Completion

December 11, 2019

Last Updated

March 18, 2020

Record last verified: 2019-02

Data Sharing

IPD Sharing
Will not share

Locations