NCT03153748

Brief Summary

This study aims at clarifying the current situation of Emergency treatment of aneurysmal subarachnoid hemorrhage (SAH) in China, and analyzing the safety and efficacy of the treatment strategy between interventional treatment and open surgery, so as to improve the diagnosis and treatment of aneurysmal SAH.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
10,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jul 2016

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2016

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

May 11, 2017

Completed
4 days until next milestone

First Posted

Study publicly available on registry

May 15, 2017

Completed
3.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2020

Completed
Last Updated

May 15, 2017

Status Verified

May 1, 2017

Enrollment Period

4.5 years

First QC Date

May 11, 2017

Last Update Submit

May 12, 2017

Conditions

Keywords

Treatment strategy

Outcome Measures

Primary Outcomes (2)

  • mRS score

    the mRS score after treatment

    1 year after treatment

  • cure rate

    the proportion of the cured-patient according Raymond Class

    6 months after treatment

Secondary Outcomes (2)

  • recurrence rate

    through study completion, an average of 1 year

  • complication rate

    through study completion, an average of 1 year

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

patients presented with subarachnoid hemorrhage and diagnosed with ruptured aneurysm at all age.

You may qualify if:

  • patients presented with subarachnoid hemorrhage on CT or lumbar puncture.
  • the intracranial hemorrhage was caused by rupture of aneurysm and was confirmed on CTA、MRA or DSA.
  • patients willing to participate in this clinical trial and attach to regular follow up.

You may not qualify if:

  • intracranial aneurysm correlating to AVM.
  • dissection, false, traumatic and infectious aneurysms.
  • the rupture of the aneurysm can not be confirmed on CTA、MRA or DSA.
  • patients unwilling to participate in this clinical trial and attach to regular follow up.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Changhai Hospital

Shanghai, Shanghai Municipality, 200433, China

RECRUITING

MeSH Terms

Conditions

Subarachnoid Hemorrhage

Condition Hierarchy (Ancestors)

Intracranial HemorrhagesCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular DiseasesHemorrhagePathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Qinghai Huang, MD

    Changhai Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Pengfei Yang, MD

CONTACT

Hongjian Zhang, MD

CONTACT

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Target Duration
1 Year
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

May 11, 2017

First Posted

May 15, 2017

Study Start

July 1, 2016

Primary Completion

December 31, 2020

Study Completion

December 31, 2020

Last Updated

May 15, 2017

Record last verified: 2017-05

Data Sharing

IPD Sharing
Will not share

Locations