Rhythmic Motor Learning in Children With Developmental Coordination Disorders
EPIC2
Brain Plasticity and Motor Skill Competence Development in Young People With Development Coordination Disorder
1 other identifier
interventional
87
1 country
5
Brief Summary
The importance of play and physical activity include many benefits on positively improving health and well-being, enhancing children's and young people's thinking and performance in school, improving their sleep and enabling confidence and skill building. However, some children find it hard to learn and perform motor skills, and are at risk of decreased participation in sports and physical activity and subsequently decreased physical fitness and overall health and well-being. Previous studies from the research group have explored the impact and recovery following acute exercise at different intensities in children and adolescents with and without movement difficulties. Following this, a pathway promoting physical activity and engagement has been successfully established within schools for those with and without movement difficulties. Taking the previous studies further, we want to specifically focus on the children's performance and learning of a sporting skill, such as stepping, and the associated brain activity changes, using available high resolution imaging techniques. This will help us understand how these children perform and learn motor and sporting skills. Evidence obtained from imaging alongside measures of movement has helped the development of optimal therapeutic approaches for other conditions such as stroke and Parkinson's and will help us to develop approaches to help children best learn motor skills and hence gain confidence in performing sporting activities.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Oct 2016
Typical duration for not_applicable
5 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2016
CompletedFirst Submitted
Initial submission to the registry
April 4, 2017
CompletedFirst Posted
Study publicly available on registry
May 12, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2018
CompletedMay 30, 2018
May 1, 2018
1.8 years
April 4, 2017
May 25, 2018
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Novel Stepping Task (assessing change over time)
Rhythmic stepping task measuring coordination
Baseline - change from baseline 6-7 weeks - change from baseline 12 weeks
Functional Near-Infra red Spectroscopy (FNIRs) (assessing change over time)
Monitoring haemodynamic change of the cortex
Baseline - change from baseline 6-7 weeks - change from baseline 12 weeks
Secondary Outcomes (7)
Physical Activity Audit (PAQ-A) (assessing change over time)
Baseline - change from baseline 6-7 weeks - change from baseline 12 weeks
Functional Magnetic Resonance Imaging (FMRI) (assessing change over time)
Baseline - change from baseline 6-7 weeks
Movement Assessment Battery for Children 2
Baseline
Inertial Measurement Unit (IMU)
Baseline - change from baseline 6-7 weeks - change from baseline 12 weeks
Child Health Utility Questionnaire 9D (assessing change over time)
Baseline - change from baseline 6-7 weeks - change from baseline 12 weeks
- +2 more secondary outcomes
Study Arms (2)
Motor coordination difficulties
EXPERIMENTALType: Experimental main EPIC club: 60min session / 2 times weekly / 7 weeks
Non motor coordination difficulties
OTHERType: Experimental comparator EPIC club: 60min session / 2 times weekly / 7 weeks
Interventions
Weekly exercise gym sessions. Participants will start with a warm-up of 20-25 mins cardiovascular training either doing cycling, treadmill running or cross-training. The remainder of the session consists of strength/resistance and weight-training involving leg press, leg extensor, pull downs, kettle bells, dumbbells. In addition to the above, a novel rhythmical stepping task will be performed over 10 mins.
Eligibility Criteria
You may qualify if:
- years old children (year 9 students only) with normal intelligence in the lowest quartile of fitness (30 with poor motor skill acquisition and performance affecting daily functioning, 30 who score in the lower 25% of fitness measures without poor motor skill acquisition and execution).
You may not qualify if:
- Behavioural/intellectual issues that prevent safe participation or may put the participant, investigators and others at risk.
- Any contraindications to perform maximal exercise or physical training, as determined by the Physical Activity Health Questionnaire PARQ sent out to parents before screening.
- Children suffering from muscular/neurological degenerative conditions or with uncontrolled epilepsy/seizures (must be stable epilepsy/on medication for greater than 12 weeks).
- Surgical procedures in the previous 6 months.
- If there are any concerns regarding a child being able to participate safely, we will ask parents/guardians to contact the GP/paediatrician/physiotherapist.
- MRI Scanner: children with metal objects due to surgery or dental care cannot partake in the scanning part of the research.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Oxford Brookes Universitylead
- University of Oxfordcollaborator
- National University of Ireland, Maynoothcollaborator
Study Sites (5)
Cherwell School
Oxford, OXON, OX2 7EE, United Kingdom
Clinical Exercise Rehabilitation Unit
Oxford, OXON, OX3 0BP, United Kingdom
Oxford Brookes University
Oxford, OXON, OX3 0BP, United Kingdom
Cheney School
Oxford, OXON, OX3 7QH, United Kingdom
Wheatley Park School
Oxford, OXON, OX33 1QH, United Kingdom
Related Publications (2)
Liu YC, Esser P, Weedon BD, Springett D, Joshi S, Tsou MH, Wang RY, Dawes H. Knee joint position sense and kinematic control in relation to motor competency in 13 to 14-year-old adolescents. Ital J Pediatr. 2024 Sep 29;50(1):200. doi: 10.1186/s13052-024-01765-z.
PMID: 39343969DERIVEDInacio M, Esser P, Weedon BD, Joshi S, Meaney A, Delextrat A, Springett D, Kemp S, Ward T, Izadi H, Johansen-Berg H, Dawes H. Learning a novel rhythmic stepping task in children with probable developmental coordination disorder. Clin Biomech (Bristol). 2023 Feb;102:105904. doi: 10.1016/j.clinbiomech.2023.105904. Epub 2023 Feb 3.
PMID: 36764101DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- BASIC SCIENCE
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor, Movement Science Group, Faculty of Health and Life Sciences, Oxford Brookes University
Study Record Dates
First Submitted
April 4, 2017
First Posted
May 12, 2017
Study Start
October 1, 2016
Primary Completion
August 1, 2018
Study Completion
August 1, 2018
Last Updated
May 30, 2018
Record last verified: 2018-05
Data Sharing
- IPD Sharing
- Will not share
As per ethical outline, data will not be stored in a shared repository. All data will be stored in an anonymised format on site. Data access requests should be made to the principle investigator in writing which will be discussed in the data monitoring committee meetings.