Study of microRNAs in the Evolution of Carotid Plaque. Physiopathological and Therapeutic Interest
1 other identifier
observational
245
1 country
1
Brief Summary
Carotid stenosis of atherosclerotic origin may be responsible for stroke, which is one of the most important causes of morbidity and mortality in the Western world
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Dec 2012
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 26, 2012
CompletedFirst Submitted
Initial submission to the registry
May 4, 2017
CompletedFirst Posted
Study publicly available on registry
May 11, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 26, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
December 26, 2020
CompletedAugust 3, 2018
August 1, 2018
8 years
May 4, 2017
August 2, 2018
Conditions
Outcome Measures
Primary Outcomes (1)
Analysis of the miRNAs
by PCR of the composition of the atheroma plaque
3 years
Study Arms (2)
Symptomatic patients
in the department with carotid plaque Comparing the expression of miRNAs
Asymptomatic patients
in consultation with carotid plaque Comparing the expression of miRNAs
Interventions
by PCR, in symptomatic and asymptomatic carotid plaques.
Eligibility Criteria
Symptomatic patients in the service, and asymptomatic in consultation with carotid atheroma plaque
You may qualify if:
- Any adult with a carotid thrombo endarterectomy,
- affiliated to a social security scheme,
- informed of the study and not opposed to it.
You may not qualify if:
- Any person benefiting from an iterative carotid surgery,
- or refusing to participate in the study,
- or not being able to express its consent.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
CHU Amiens Picardie
Amiens, Picardie, 80054, France
Study Officials
- PRINCIPAL INVESTIGATOR
Thierry REIX, PhD
CHU AMIENS-PICARDIE
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
May 4, 2017
First Posted
May 11, 2017
Study Start
December 26, 2012
Primary Completion
December 26, 2020
Study Completion
December 26, 2020
Last Updated
August 3, 2018
Record last verified: 2018-08