NCT03129334

Brief Summary

This project is designed to test a primary prevention approach to the problem of prescription drug misuse and abuse (PDA) among middle school students. The intervention uses both online e-learning and small group facilitator-led intervention modalities. Middle schools will be randomized to receive the intervention or serve as controls.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
4,500

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Sep 2015

Longer than P75 for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2015

Completed
1.6 years until next milestone

First Submitted

Initial submission to the registry

April 17, 2017

Completed
9 days until next milestone

First Posted

Study publicly available on registry

April 26, 2017

Completed
3.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2020

Completed
Last Updated

February 25, 2020

Status Verified

February 1, 2020

Enrollment Period

4.8 years

First QC Date

April 17, 2017

Last Update Submit

February 24, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change in any prescription drug use in the past year

    The investigators will assess (via questionnaire) key study variables regarding prescription drug abuse and hypothesized risk and protective factors. These outcomes will be examined and compared in both the intervention group and the control group at a post-test assessment and 6- and 12-month follow-up assessments.

    Post-test (within 2 weeks of completing final session/module of the intervention), 6-month followup, 12-month followup

Study Arms (2)

LST Middle School Online

EXPERIMENTAL

Students will participate in a series of e-learning modules plus classroom sessions related to drug abuse prevention, including prescription drug abuse

Behavioral: LST Middle School Online

Treatment as Usual (Control)

NO INTERVENTION

Students will not participate in the e-learning modules. They will receive any standard classroom instruction on drug abuse/health education.

Interventions

The adapted intervention will (1) utilize both online e-learning module (self-guided) and classroom-based sessions (facilitator led) to address PDA and concurrent ATOD abuse; (2) positively change social norms and challenge positive expectancies regarding PDA and ATOD abuse; (3) discourage diversion of prescription medications; (4) enhance protective factors by building social and self-regulation skills through interactive learning and behavioral rehearsal scenarios; and (5) incorporate booster sessions.

LST Middle School Online

Eligibility Criteria

Age11 Years - 14 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Middle school aged-youth

You may not qualify if:

  • Significant cognitive impairment or severe learning disabilities, as screened by field staff at participating sites

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Substance-Related Disorders

Condition Hierarchy (Ancestors)

Chemically-Induced DisordersMental Disorders

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Senior Research Scientiest

Study Record Dates

First Submitted

April 17, 2017

First Posted

April 26, 2017

Study Start

September 1, 2015

Primary Completion

June 1, 2020

Study Completion

June 1, 2020

Last Updated

February 25, 2020

Record last verified: 2020-02

Data Sharing

IPD Sharing
Will not share