NCT03129230

Brief Summary

This study was to evaluate the safety and efficacy of free nonvascularized fibula autograft in the treatment of the femoral neck tumor-like lesions before epiphyseal closure in pediatric patients, by presenting the clinic-radiological outcome and complications.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
16

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Aug 2012

Longer than P75 for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2012

Completed
4.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2016

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2017

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

April 5, 2017

Completed
21 days until next milestone

First Posted

Study publicly available on registry

April 26, 2017

Completed
Last Updated

November 27, 2018

Status Verified

November 1, 2018

Enrollment Period

4.1 years

First QC Date

April 5, 2017

Last Update Submit

November 25, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • change of peri-implant bone level from baseline at 7 and 54 months

    Mean follow-up of all the patients after primary surgery was 24 months, ranged 7 months to 54 months.

    7 months to 54 months

Study Arms (1)

Free nonvascularized fibula autograft

EXPERIMENTAL

Sixteen pediatric patients before epiphyseal closure were treated with free nonvascularized fibula autograft after resections of tumor-like lesions in the femoral neck.

Procedure: free nonvascularized fibula autograft

Interventions

Sixteen pediatric patients before epiphyseal closure were treated with free nonvascularized fibula autograft after resections of tumor-like lesions in the femoral neck between Aug. 2012 and Sep. 2016. All the patients were given supplementary skeletal traction through supracondyle of femur for 4 weeks to 6 weeks after the resections.

Free nonvascularized fibula autograft

Eligibility Criteria

Age7 Years - 13 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • \. This retrospective study included pediatric patients before epiphyseal closure with tumor-like lesions in femoral neck.

You may not qualify if:

  • pediatric patients with tumor-like lesions in femoral neck after epiphyseal closure;
  • pediatric patients with benign bone tumors and malignant bone tumors in the femoral neck after epiphyseal closure;
  • adult patients with benign or malignant bone tumors and tumor-like lesions in femoral neck.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

The First Affiliated Hospital of Guangxi Medical University

Nanning, Guangxi, 530021, China

Location

Yulin Orthopedics Hospital of Chinese and Western Medicine

Yulin, Guangxi, China

Location

MeSH Terms

Conditions

Bone Diseases

Condition Hierarchy (Ancestors)

Musculoskeletal Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Director

Study Record Dates

First Submitted

April 5, 2017

First Posted

April 26, 2017

Study Start

August 1, 2012

Primary Completion

September 1, 2016

Study Completion

March 1, 2017

Last Updated

November 27, 2018

Record last verified: 2018-11

Data Sharing

IPD Sharing
Will not share

Locations