NCT03120923

Brief Summary

This study aims to assess and compare the effectiveness of two different volumes of local anesthetic combined with 40mg of triamcinolone for subacromial injections in treating patients with rotator cuff impingement syndrome

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
52

participants targeted

Target at P25-P50 for phase_4

Timeline
Completed

Started Jan 2015

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2015

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2016

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

April 16, 2017

Completed
3 days until next milestone

First Posted

Study publicly available on registry

April 19, 2017

Completed
Last Updated

October 18, 2017

Status Verified

October 1, 2017

Enrollment Period

1.6 years

First QC Date

April 16, 2017

Last Update Submit

October 17, 2017

Conditions

Keywords

subacromial injection

Outcome Measures

Primary Outcomes (1)

  • VAS

    Visual analog score

    8 weeks

Secondary Outcomes (2)

  • WORC

    8 weeks

  • Adverse reaction

    8 weeks

Study Arms (2)

Lidocaine 3 cc & Triamcinolone Acetonide

EXPERIMENTAL
Drug: Lidocaine 3 ccDrug: Triamcinolone Acetonide

Lidocaine 9cc & Triamcinolone Acetonide

ACTIVE COMPARATOR
Drug: Lidocaine 9 ccDrug: Triamcinolone Acetonide

Interventions

Lidocaine 3 cc & Triamcinolone Acetonide

9mL of 1% lidocaine plus 1mL of 40mg triamcinolone acetonide

Lidocaine 9cc & Triamcinolone Acetonide
Lidocaine 3 cc & Triamcinolone AcetonideLidocaine 9cc & Triamcinolone Acetonide

Eligibility Criteria

Age20 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • participants with clinically diagnosed the rotator cuff impingement
  • participants aged 20 years and older
  • at least 1 month's duration
  • pain of moderate to severe intensity, defined as a score of 5 or more points on a 10-cm visual analog scale (VAS) rated from 0 (no pain) to 10 (worst imaginable pain)

You may not qualify if:

  • patients with adhesive capsulitis of the shoulder (normal radiograph of affected shoulder, and restriction of passive motion \>30° in ≥2 planes of movement)
  • previous trauma history at currently affected shoulder
  • previous corticosteroid injection history at the affected shoulder
  • abnormal calcification and/or primary osteoarthritis of the shoulder joint on plain radiographs
  • use of medication such as antiplatelet agent or anticoagulation.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Boonard M, Sumanont S, Arirachakaran A, Apiwatanakul P, Boonrod A, Kanchanatawan W, Kongtharvonskul J. Short-term outcomes of subacromial injection of combined corticosteroid with low-volume compared to high-volume local anesthetic for rotator cuff impingement syndrome: a randomized controlled non-inferiority trial. Eur J Orthop Surg Traumatol. 2018 Aug;28(6):1079-1087. doi: 10.1007/s00590-018-2149-3. Epub 2018 Feb 8.

MeSH Terms

Conditions

Shoulder Impingement Syndrome

Interventions

Triamcinolone Acetonide

Condition Hierarchy (Ancestors)

Joint DiseasesMusculoskeletal DiseasesShoulder InjuriesWounds and Injuries

Intervention Hierarchy (Ancestors)

TriamcinolonePregnadienesPregnanesSteroidsFused-Ring CompoundsPolycyclic CompoundsSteroids, Fluorinated

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr

Study Record Dates

First Submitted

April 16, 2017

First Posted

April 19, 2017

Study Start

January 1, 2015

Primary Completion

August 1, 2016

Study Completion

August 1, 2016

Last Updated

October 18, 2017

Record last verified: 2017-10