NCT03120429

Brief Summary

the aim of present study is to compare the specific effects moderate consumption of lean fish on weight loss of healthy obese and overweight female adults, while participants follow energy-restricted diets also to investigate the effects of this intervention on carbohydrate and lipid profiles, as cardiometabolic risk factors.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
120

participants targeted

Target at P50-P75 for not_applicable obesity

Timeline
Completed

Started Jun 2017

Typical duration for not_applicable obesity

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 15, 2017

Completed
4 days until next milestone

First Posted

Study publicly available on registry

April 19, 2017

Completed
2 months until next milestone

Study Start

First participant enrolled

June 25, 2017

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 22, 2019

Completed
9 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 13, 2019

Completed
Last Updated

October 25, 2019

Status Verified

October 1, 2019

Enrollment Period

1.6 years

First QC Date

April 15, 2017

Last Update Submit

October 24, 2019

Conditions

Keywords

lean fishweight lossDiet

Outcome Measures

Primary Outcomes (1)

  • weight loss

    kg

    24 Weeks

Secondary Outcomes (7)

  • waist circumference

    24 Weeks

  • fasting plasma glucose

    24 Weeks

  • serum insulin level

    24 Weeks

  • insulin resistance (HOMA-IR)

    24 Weeks

  • glycosylated hemoglobin (HbA1c)

    24 Weeks

  • +2 more secondary outcomes

Study Arms (2)

Fish group

EXPERIMENTAL

subjects will have 3 x 150 g lean fish/ week at main meal

Behavioral: Fish group

Control group

EXPERIMENTAL

subjects will have no seafood.

Behavioral: Control group

Interventions

Fish groupBEHAVIORAL

Fish group will have hypoenergetic diet in which subjects will have 3 x 150 g lean fish/ week at main meal

Also known as: FG
Fish group
Control groupBEHAVIORAL

Control group will have hypo-energetic diet in which subjects have no seafood.

Also known as: CG
Control group

Eligibility Criteria

Age18 Years - 45 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • female
  • years of age.
  • Body mass index (BMI) between 27.5-35 kg/m²
  • Must be able to have moderate exercise.
  • Must be interested to lose weight

You may not qualify if:

  • Pregnancy or lactation during the previous 6 months, or planned pregnancy in the next six months.
  • Taking medications that could affect metabolism or change body weight.
  • Report heart problems, chest pain, and cancer within the last five years.
  • Use of supplements containing n-3 fatty acids, calcium or vitamin-D during the last 3 months.
  • Consumption of fish and sea foods regularly
  • Smoking
  • Menopause
  • Diagnosis of any chronic disease such as fatty liver, cancer, chemo/radio therapy, heart disease, immune compromised conditions, abnormal thyroid hormone level.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

NovinDiet Clinic

Tehran, Iran

Location

MeSH Terms

Conditions

ObesityOverweightWeight Loss

Interventions

Control Groups

Condition Hierarchy (Ancestors)

OvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and SymptomsBody Weight Changes

Intervention Hierarchy (Ancestors)

Epidemiologic Research DesignEpidemiologic MethodsInvestigative TechniquesResearch DesignMethods

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 15, 2017

First Posted

April 19, 2017

Study Start

June 25, 2017

Primary Completion

January 22, 2019

Study Completion

October 13, 2019

Last Updated

October 25, 2019

Record last verified: 2019-10

Locations