NCT03118245

Brief Summary

Children aged below 7 years are randomly assigned to AuraGain Group or I-gel group. After anesthetic induction, AuraGain or I-gel is inserted and mechanical ventilation is started. Oropharyngeal leak pressure, peak inspiratory pressure, success rate for insertion, ease for insertion, ease for gastric tube insertion and fiberoptic bronchoscopic views will be compared between two groups.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
94

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jun 2017

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 9, 2017

Completed
9 days until next milestone

First Posted

Study publicly available on registry

April 18, 2017

Completed
2 months until next milestone

Study Start

First participant enrolled

June 12, 2017

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 31, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 31, 2018

Completed
Last Updated

September 6, 2018

Status Verified

September 1, 2018

Enrollment Period

12 months

First QC Date

April 9, 2017

Last Update Submit

September 4, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • Oropharyngeal leak pressure

    The airway pressure at which a leak sound is detected around the patient's mouth and at which the airway pressure has reached equilibrium, when the pressure-limiting valve of the anesthesia breathing system is closed and the fresh gas flow rate is fixed at 3 liter/min

    30 seconds after AuraGain or I-gel insertion

Secondary Outcomes (5)

  • Peak inspiratory pressure

    through study completion, an average of 1 hour

  • Success rate

    Within 5 minutes after anesthetic induction

  • Ease of AuraGain or I-gel insertion

    Within 5 minutes after anesthetic induction

  • Ease of gastric tube insertion

    Within 5 minutes after anesthetic induction

  • fiberoptic bronchoscopic veiw

    Within 10 minutes after anesthetic induction

Study Arms (2)

AuraGain group

EXPERIMENTAL

AuraGain is inserted for maintenance of general anesthesia. The size 1 is for children \<5kg, size 2 for 5-10kg, size 2 for 10-20kg, and size 2.5 for 20-30kg.

Device: AuraGain

I-gel group

EXPERIMENTAL

I-gel is s inserted for maintenance of general anesthesia. The size 1 is for children weighted 2-5kg, size 2 for 5-12kg, size 2 for 10-25kg, and size 2.5 for 25-35kg.

Device: I-gel

Interventions

AuraGainDEVICE

After anesthetic induction, AuraGain is inserted in children

Also known as: Ambu AuraGain
AuraGain group
I-gelDEVICE

After anesthetic induction, I-gel is inserted in children

Also known as: I-gel supraglottic airway
I-gel group

Eligibility Criteria

AgeUp to 7 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Children \< 7 years old who scheduled for general anesthesia using supraglottic airway

You may not qualify if:

  • Children who require tracheal intubation
  • Emergency operation without nil per os
  • History of C-spine surgery or disease
  • History of Esophageal disease or surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Seoul National University Hospital

Seoul, 110-744, South Korea

Location

Study Officials

  • Jin-Tae Kim, PhD

    Seoul National University Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

April 9, 2017

First Posted

April 18, 2017

Study Start

June 12, 2017

Primary Completion

May 31, 2018

Study Completion

May 31, 2018

Last Updated

September 6, 2018

Record last verified: 2018-09

Locations