The Utility of Pulse Pressure Variation to Predict the Fluid Responsiveness During Pneumoperitoneum and Reverse-Trendelenburg Position

NCT02771067 | Completed

• 1 other identifier: 4-2016-0205
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to investigate the validity of pulse pressure variation to predict fluid responsiveness in patients undergoing robotic or laparoscopic gastrectomy.

Conditions

General Anesthesia

Outcome Measures

Primary Outcomes (1)

• Pulse pressure variation

  Ability of pulse pressure variation to predict fluid responsiveness will be evaluated.

  During the surgery. At Day 0.

Study Arms (1)

Pulse pressure variation

EXPERIMENTAL

Pulse pressure variation will be recorded via an arterial catheter after anesthetic induction, before pneumoperitoneum, after pneumoperitoneum, before infusion of 6% hydroxyethyl starch, and after infusion of 6% hydroxyethyl starch. Stroke volume will be also measured to differentiate the fluid responders.

Procedure: Fluid infusion

Interventions

Fluid infusion PROCEDURE

Fluid infusion will be performed using 6% hydroxyethyl starch. Pulse pressure variation and stroke volume will be measured before and after fluid infusion.

Pulse pressure variation

Eligibility Criteria

• Age: 19 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• adult patients aged over 19 years who are scheduled for robotic or laparoscopic gastrectomy

You may not qualify if:

• cardiac arrhythmia
• valvular heart disease
• ischemic heart disease
• left ventricular ejection fraction less than 40%
• Pulmonary disease
• esophageal disease
• upper gastrointestinal bleeding
• Body mass index more than 40 kg/m2.

Sponsors & Collaborators

• Yonsei University: lead

Study Sites (1)

Department of Anesthesiology and Pain Medicine Anesthesia and Pain Research Institute Yonsei University

Seoul, 120-752, South Korea

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 4, 2016
• First Posted: May 12, 2016
• Study Start: September 29, 2016
• Primary Completion: February 23, 2017
• Study Completion: February 23, 2017
• Last Updated: December 18, 2017

Record last verified: 2017-12

Data Sharing

• IPD Sharing: Will not share

Locations

KR (1)