Lung Ultrasound in High Altitude Lung Edema
Estimation of Pulmonary Arterial Pressure With Transesophageal Echocardiography: A Pilot Study
1 other identifier
observational
20
1 country
1
Brief Summary
High altitude pulmonary edema is a life-threatening condition that remains a concern for climbers and clinicians alike. It is defined as a non-cardiac pulmonary edema occurring at altitudes exceeding 3000m in non-acclimatised individuals. Recently, studies conducted in remote areas have demonstrated that ultrasound lung comets (B lines) can be used as a measure of sub-acute pulmonary edema and high altitude pulmonary edema in climbers ascending to altitude. the investigators want to assess the occurrence of of comet tails (B lines) as a measure of pulmonary edema among patients after lung transplantation and healthy individuals during an expedition to Mount Kilimanjaro.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Jun 2017
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 6, 2017
CompletedFirst Posted
Study publicly available on registry
April 18, 2017
CompletedStudy Start
First participant enrolled
June 10, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 22, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
November 30, 2017
CompletedDecember 2, 2017
November 1, 2017
12 days
April 6, 2017
November 30, 2017
Conditions
Outcome Measures
Primary Outcomes (1)
lung ultrasound
Positive "B-line pattern" in patients after lung transplantations and healthy volunteers at sea level and high altitude (4600 m)
2 weeks
Secondary Outcomes (1)
optic nerve sheath diameter
2 weeks
Study Arms (2)
healthy volunteers
10 healthy volunteers climbing Mount Kilimanjaro receiving lung ultrasound
patients after lung transplantation
10 patients \> 2years after lung transplantation climbing Mount Kilimanjaro receiving lung ultrasound
Interventions
lung ultrasound with positive "B-line pattern" in patients after lung transplantations and healthy volunteers at sea level and high altitude (4600 m) at Mountb Kilimanjaro
Eligibility Criteria
10 patients \> 2 years after lung transplantation and 10 healthy volunteers during expedition to Mount Kilimanjaro
You may qualify if:
- Expedition to Mount Kilimanjaro
You may not qualify if:
- Refusal to participate in the study
- Age \< 18 years
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Medical university of vienna, General hospital of Vienna
Vienna, 1090, Austria
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Ulrike Weber, M.D.
Medical University of Vienna
Study Design
- Study Type
- observational
- Observational Model
- OTHER
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Ass.Prof.Dr.
Study Record Dates
First Submitted
April 6, 2017
First Posted
April 18, 2017
Study Start
June 10, 2017
Primary Completion
June 22, 2017
Study Completion
November 30, 2017
Last Updated
December 2, 2017
Record last verified: 2017-11
Data Sharing
- IPD Sharing
- Will not share