Trials Sponsors Conditions Drugs Pricing

Conditions

Photoaging Wrinkle

Outcome Measures

Primary Outcomes (2)

Change in Wrinkle Appearance
Assessed using image analysis based assessment of wrinkle severity (depth and length). The primary outcome measure was image-analysis-based assessment of wrinkle severity and pigmentation at 12 weeks.
12 week
Percentage of Participants With Change in Appearance of Skin Pigmentation
Assessed using image analysis based assessment of facial pigment
12 week

Secondary Outcomes (2)

Number of Reports of Stinging, Burning, Itching
Assessed at Week 4, 8, and 12.
Number of Reports of Facial Erythema Assessment
week 4, week 8 and week 12

Study Arms (2)

Bakuchiol

EXPERIMENTAL

Bakuchiol 0.5% applied to face twice daily

Drug: Bakuchiol

Retinol

ACTIVE COMPARATOR

0.5% retinol applied to face nightly

Drug: Retinol

Interventions

BakuchiolDrug

This group will receive bakuchiol

Also known as: Bakuchiol 0.5%

Bakuchiol

RetinolDrug

This group will receive retinol

Also known as: Retinol %

Eligibility Criteria

Age30 Years - 55 Years

Sexall

Healthy VolunteersYes

Age GroupsAdult (18-64)

You may qualify if:

Individuals aged 30-55

You may not qualify if:

Sponsors & Collaborators

University of California, Davis
Otherlead

Study Sites (1)

UC Davis Department of Dermatology

Sacramento, California, 95816, United States

MeSH Terms

Interventions

bakuchiolVitamin A

Intervention Hierarchy (Ancestors)

RetinoidsCarotenoidsPolyenesAlkenesHydrocarbons, AcyclicHydrocarbonsOrganic ChemicalsCyclohexenesCyclohexanesCycloparaffinsHydrocarbons, AlicyclicHydrocarbons, CyclicTerpenes

Results Point of Contact

Title: Iryna Rybak
Organization: UC Davis Dermatology

Study Officials

Raja Sivamani, MD
UC Davis
PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee: No
Restrictive Agreement: No

Enrollment

44 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: early phase 1
Allocation: RANDOMIZED
Masking: TRIPLE
Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose: TREATMENT
Intervention Model: PARALLEL
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

March 27, 2017

First Posted

April 13, 2017

Study Start

March 24, 2017

Actual (reported)

Comparison of the Cosmetic Effects of Bakuchiol and Retinol

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Results Posted

Conditions

Outcome Measures

Primary Outcomes (2)

Secondary Outcomes (2)

Study Arms (2)

Bakuchiol

Retinol

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Interventions

Intervention Hierarchy (Ancestors)

Results Point of Contact

Study Officials

Publication Agreements

Enrollment

Study Design

Study Record Dates

Source record

Documents

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Results Posted

Conditions

Outcome Measures

Primary Outcomes (2)

Secondary Outcomes (2)

Study Arms (2)

Bakuchiol

Retinol

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Interventions

Intervention Hierarchy (Ancestors)

Results Point of Contact

Study Officials

Publication Agreements

Enrollment

Study Design

Study Record Dates

Source record

Documents

Locations