NCT03111706

Brief Summary

Prospective observational study conducted on women with previous 1 or 2 CS candidate for elective CS. Ultrasonographic evaluation of lower uterine segment using 2D and 3D transabdominal and transvaginal then correlated to scar integrity assessed intraoperatively

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
300

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started May 2017

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 8, 2017

Completed
5 days until next milestone

First Posted

Study publicly available on registry

April 13, 2017

Completed
18 days until next milestone

Study Start

First participant enrolled

May 1, 2017

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2018

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2018

Completed
Last Updated

April 14, 2017

Status Verified

April 1, 2017

Enrollment Period

1 year

First QC Date

April 8, 2017

Last Update Submit

April 13, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Scar dehiscence

    as the presence of either transparent LUS with visible contents, presence of well-circumscribed scar defect or presence of frank uterine rupture.

    At time of surgery

Study Arms (2)

dehiscencd scar

women who are discovered with scar dehiscence during cesarean section

Procedure: Cesarean section

Intact scar

women with intact scar detected during cesarean section

Procedure: Cesarean section

Interventions

During Cesarean delivery the lower uterine segment (LUS) was defined as the part of the uterus below the uterovesical peritoneal reflection. After opening the visceral peritoneum and performing the bladder dissection, the LUS was assessed for integrity of the CS scar by the operating surgeon to avoid bias by the sonographic findings. Scar dehiscence was defined as the presence of either transparent LUS with visible contents, presence of well-circumscribed scar defect or presence of frank uterine rupture.

Intact scardehiscencd scar

Eligibility Criteria

Age19 Years - 44 Years
Sexfemale(Gender-based eligibility)
Healthy VolunteersNo
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

women with prior 1 or 2 cesarean sections candidate for elective cesarean sewction

You may qualify if:

  • weeks of gestational age
  • singleton pregnancy,
  • cephalic presentation,
  • not in labor
  • intact membranes
  • with history of one or two previous CS

You may not qualify if:

  • disorders of amniotic fluid,
  • placenta previa
  • history of other uterine surgery, e.g, myomectomy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Kasr Alainy medical school

Cairo, Cairo Governorate, 12151, Egypt

Location

MeSH Terms

Interventions

Cesarean Section

Intervention Hierarchy (Ancestors)

Delivery, ObstetricObstetric Surgical ProceduresSurgical Procedures, Operative

Study Officials

  • Ahmed Maged, MD

    Kasr Alainy medical school

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Mona Fouad, MD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

April 8, 2017

First Posted

April 13, 2017

Study Start

May 1, 2017

Primary Completion

May 1, 2018

Study Completion

July 1, 2018

Last Updated

April 14, 2017

Record last verified: 2017-04

Locations