NCT03111173

Brief Summary

This is a feasibility study for a new application for capturing fetal cardiac activity. The objective of this study is to determine if it is feasible to capture a fetal ECG signal using a Holter ECG device. As comparison we will use a standard Doppler Fetal Heart Rate (FHR) device.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
7mo left

Started Jun 2017

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress94%
Jun 2017Dec 2026

First Submitted

Initial submission to the registry

April 7, 2017

Completed
5 days until next milestone

First Posted

Study publicly available on registry

April 12, 2017

Completed
2 months until next milestone

Study Start

First participant enrolled

June 2, 2017

Completed
8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2025

Completed
1.5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2026

Expected
Last Updated

January 18, 2024

Status Verified

January 1, 2024

Enrollment Period

8 years

First QC Date

April 7, 2017

Last Update Submit

January 16, 2024

Conditions

Keywords

ECGFetusR peak extraction

Outcome Measures

Primary Outcomes (1)

  • Successful extraction of fetal ECG from the maternal abdominal ECG signal

    We will test the quality of correct identification of fetal R peaks of ECG from within maternal ECG signal by comparing the R-R-periods-derived instantaneous fetal heart rate (FHR) to the values determined by the standard-of-care ultrasound-derived FHR monitor.

    12 months

Study Arms (1)

Holter device

OTHER

Holter device to be attached to a Singleton or twin pregnant women at 32 weeks gestation to full term

Device: Holter Device

Interventions

MyECG E3.80 Holter Recorder

Holter device

Eligibility Criteria

Age18 Years - 55 Years
Sexfemale(Gender-based eligibility)
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Singleton or twin pregnant women at 32 weeks gestation to full term after routine antepartum testing.

You may not qualify if:

  • None.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Washington

Seattle, Washington, 98105, United States

RECRUITING

Related Publications (1)

  • Efficient fetal-maternal ECG signal separation from two channel maternal abdominal ECG via diffusion-based channel selection Ruilin Li, Martin G. Frasch, Hau-tieng Wu (Submitted on 7 Feb 2017) There is a need for affordable, widely deployable maternal-fetal ECG monitors to improve maternal and fetal health during pregnancy and delivery. Based on the diffusion-based channel selection, here we present the mathematical formalism and clinical validation of an algorithm capable of accurate separation of maternal and fetal ECG from a two channel signal acquired over maternal abdomen. Subjects: Medical Physics (physics.med-ph); Data Analysis, Statistics and Probability (physics.data-an); Applications (stat.AP); Machine Learning (stat.ML) Cite as: arXiv:1702.02025 [physics.med-ph]

    BACKGROUND

Related Links

Study Officials

  • Martin G Frasch, MD, PhD

    University of Washington

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Martin G Frasch, MD, PhD

CONTACT

Amy Gest, MPA

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DEVICE FEASIBILITY
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Research Assistant Professor, Obstetrics and Gynecology

Study Record Dates

First Submitted

April 7, 2017

First Posted

April 12, 2017

Study Start

June 2, 2017

Primary Completion

June 1, 2025

Study Completion (Estimated)

December 1, 2026

Last Updated

January 18, 2024

Record last verified: 2024-01

Data Sharing

IPD Sharing
Will not share

Locations