NCT03107728

Brief Summary

The purpose of the IM ABLE(Injuries Managed with Advanced Bracing for Lower Extremities) study is to determine if advanced (ADV) ankle foot orthoses (AFOs) will enable users to achieve greater levels of physical and self-reported function compared with conventional (CONV) AFOs for those ambulating at or above the independent community level of ambulation.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
120

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Feb 2018

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 29, 2017

Completed
13 days until next milestone

First Posted

Study publicly available on registry

April 11, 2017

Completed
11 months until next milestone

Study Start

First participant enrolled

February 22, 2018

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2019

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2019

Completed
Last Updated

March 20, 2019

Status Verified

March 1, 2019

Enrollment Period

1.3 years

First QC Date

March 29, 2017

Last Update Submit

March 18, 2019

Conditions

Keywords

orthoticshigh-energy lower extremity traumaphysical therapybracingfunctional performanceperformance assessment

Outcome Measures

Primary Outcomes (2)

  • Change in Mobility

    Mobility will be assessed with the Timed Up \& Go test. subjects are timed while they rise from a chair, walk 3m, turn around, return to the chair and sit down again. Patients are usually permitted to use a walking aid, but not to use physical assistance.

    Mobility will be assessed at Week 2 and Week 4

  • Change in Ambulatory Function

    The 2 Minute Walk Test will be used to assess ambulatory function

    Ambulatory Function will be assessed at week 2 and week 4.

Secondary Outcomes (3)

  • Perceived Function

    At week 2 and week 4

  • Pain

    At week 2 and week 4

  • Safety will be measured with the Activities Balance Confidence Scale

    At week 2 and week 4

Study Arms (2)

Advanced orthotic brace

EXPERIMENTAL
Device: Advanced orthotic brace

Conventional orthotic brace

ACTIVE COMPARATOR
Device: Conventional orthotic brace

Interventions

Participants will use an advanced exoskeletal orthosis.

Advanced orthotic brace

Participants will use the standard of care orthosis

Conventional orthotic brace

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Lower extremity injury of any etiology requiring use of an AFO
  • Male or Female, of any ethnicity
  • yrs of age
  • lbs
  • ≥ 1 yr. of orthotic experience

You may not qualify if:

  • Body weight \<100 or \>275 lbs
  • Does not speak English or Spanish
  • Known cognitive impairment (i.e. Diagnoses such as Traumatic Brain Injury, Dementia)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

New York VA

New York, New York, 10010, United States

RECRUITING

Hanger, Inc

Houston, Texas, 77025, United States

RECRUITING

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

March 29, 2017

First Posted

April 11, 2017

Study Start

February 22, 2018

Primary Completion

June 1, 2019

Study Completion

September 1, 2019

Last Updated

March 20, 2019

Record last verified: 2019-03

Locations