NCT03101410

Brief Summary

This clinical project aims to study the relationship between gluten consumption and its impact on digestive comfort, quality of life and performance of non-celiac athletes practicing an intensive physical activity..

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
51

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Apr 2017

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 9, 2017

Completed
23 days until next milestone

Study Start

First participant enrolled

April 1, 2017

Completed
4 days until next milestone

First Posted

Study publicly available on registry

April 5, 2017

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 21, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 21, 2018

Completed
Last Updated

June 11, 2018

Status Verified

June 1, 2018

Enrollment Period

12 months

First QC Date

March 9, 2017

Last Update Submit

June 8, 2018

Conditions

Keywords

Glutensport performance

Outcome Measures

Primary Outcomes (1)

  • Food Benefits Assessment (FBA)

    at the beginning of the study, at 2 month and 4 month

Secondary Outcomes (7)

  • Physicals performances assessment : 3000m running performance

    at the beginning of the study, at 2 month and 4 month

  • Microbiota composition analysis on faeces samples

    at the beginning of the study, at 2 month and 4 month

  • Changes in body composition measured by bioelectrical impedance

    at the beginning of the study, at 2 month and 4 month

  • Qualities life index for digestive disorders modified (GIQLI assessment modified)

    at the beginning of the study, at 2 month and 4 month

  • Inflammatory cytokines

    at the beginning of the study, at 2 month and 4 month

  • +2 more secondary outcomes

Study Arms (2)

gluten

EXPERIMENTAL

Selected participants will be randomly allocated to treatment group (gluten or gluten free)

Behavioral: Gluten

gluten fee

EXPERIMENTAL

Selected participants will be randomly allocated to treatment group (gluten or gluten free)

Behavioral: Gluten free

Interventions

GlutenBEHAVIORAL

Selected participants will be randomly allocated to treatment group (gluten or gluten free).

gluten
Gluten freeBEHAVIORAL

Selected participants will be randomly allocated to treatment group (gluten or gluten free).

gluten fee

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Male and female trained \>7h/week or more of 5 training/week
  • Member of a sports federation or medical certificate fewer 3 months
  • VO2 max estimated \>125% of the theoretical value
  • Regular consumption of gluten under different products
  • Healthy (apparently free of diseases) and without any medical treatment
  • Without digestive diseases and non-coeliac disease
  • Affiliated to National Health Insurance
  • Having normal capacity of training to enter in the study procedures
  • Having provided her written informed consent

You may not qualify if:

  • Medicals or surgical histories, evaluated non compatible by the investigator
  • Diseases known
  • Antibiotherapy 2 months before the study
  • Gluten-free diet
  • Individual unable to give informed consent or refusing to sign informed consent
  • Currently participating or who having got 4500€ in this year before to have participating in another clinical trial

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHU Clermont-Ferrand

Clermont-Ferrand, 63003, France

Location

MeSH Terms

Conditions

Intestinal Diseases

Interventions

GlutensDiet, Gluten-Free

Condition Hierarchy (Ancestors)

Gastrointestinal DiseasesDigestive System Diseases

Intervention Hierarchy (Ancestors)

ProlaminsGrain ProteinsPlant ProteinsProteinsAmino Acids, Peptides, and ProteinsSeed Storage ProteinsDiet TherapyNutrition TherapyTherapeuticsDietNutritional Physiological PhenomenaDiet, Food, and NutritionPhysiological Phenomena

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Masking Details
single blind
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 9, 2017

First Posted

April 5, 2017

Study Start

April 1, 2017

Primary Completion

March 21, 2018

Study Completion

March 21, 2018

Last Updated

June 11, 2018

Record last verified: 2018-06

Locations