Impact of Air Quality on Exacerbations of COPD in the Somme

NCT03079661 | Terminated

• 1 other identifier: RNI2016-42
• Study Type: observational
• Target: 179
• Locations: 1 country
• Sites: 1

Brief Summary

All COPD patients with a diagnosis of acute exacerbation in emergency room in University Hospital of Amiens-Picardie between 01/01/2017 and 31/12/2017. The investigator will collect for each patient the home address and the work address. The duration of 1 year was chosen to take into account seasonal variations. In parallel, a daily report of the rate of ozone, particles (PM2.5 and PM10), dioxide nitrogen but also odours and pollens will be done by ATMO Picardie.

Conditions

Acute Exacerbation Copd

Keywords

pollution; ozone; Copd; particles

Outcome Measures

Primary Outcomes (1)

• exacerbation rate : variable to be explicated with explicative variable : ozone, particles, dioxide nitrogen, but also pollens corresponding to each patient home address for period of exacerbation

  exacerbation rate : variable to be explicated with explicative variable : ozone, particles, dioxide nitrogen, but also pollens corresponding to each patient home address for period of exacerbation

  1 day

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The primary endpoint is the number of exacerbations of COPD corresponding to the variable of interest to be explained. The other variables are the explanatory variables (air quality data PM2.5, PM10, NO2, O3 as well as pollen data, seasonal variations, influenza epidemic and olfactory nuisance). The final diagnosis will also be collected.

You may qualify if:

• All COPD patients with a diagnosis of acute exacerbation of COPD in the emergency room. The definition of COPD and acute exacerbation are the official definition of the Société de Pneumologie en Langue Française.

Sponsors & Collaborators

• Centre Hospitalier Universitaire, Amiens: lead

Study Sites (1)

CHU Amiens Picardie

Amiens, Picardie, 80054, France

Location

Related Publications (1)

• Basille D, Soriot L, Weppe F, Desmettres P, Henriques P, Benoit N, Devaux S, Diouf M, Jounieaux V, Andrejak C. Association between acute exacerbation of chronic obstructive pulmonary disease and short-term exposure to ambient air pollutants in France. Environ Health. 2024 Nov 29;23(1):107. doi: 10.1186/s12940-024-01146-3.

  PMID: 39614356 DERIVED

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 9, 2017
• First Posted: March 14, 2017
• Study Start: January 1, 2017
• Primary Completion: January 14, 2019
• Study Completion: January 14, 2019
• Last Updated: July 15, 2020

Record last verified: 2020-07

Locations

FR (1)