The Effect of a Protein Hydrolysate on Muscle Strength Recovery

NCT03063346 | Completed

• 1 other identifier: MU-001
• Study Type: interventional
• Target: 48
• Locations: 0 countries
• Sites: N/A

Brief Summary

Overtraining is a real problem for (semi-)professional athletes. Overtraining is often caused by the bodies' lack of ability to recover between training. In addition, during high intensity training reactive oxygen species are formed up to 20 fold compared to resting values. This causes increased muscle tissue damage after intense exercise, which slows down recovery. Improving recovery may increase an athlete's ability to reach higher training volumes resulting in establishing a higher performance plateau. It is known that hydrolyzed proteins have a positive effect on muscle protein synthesis due to its faster absorption rate. Therefore, it is hypothesized that a known protein hydrolysate may have positive effects on strength recovery.

Conditions

Muscle Strength Recovery

Outcome Measures

Primary Outcomes (1)

• Muscle strength recovery

  difference in peak force between the exhaustion challenge and the recovery challenge, measured with a linear encoder during a squat exercise

  4 weeks

Secondary Outcomes (4)

• Blood lactate buildup

  4 weeks

• Body composition

  4 weeks

• Exercise volume

  4 weeks

• Peak force output

  4 weeks

Study Arms (3)

Protein hydrolysate high dose

EXPERIMENTAL

Dietary Supplement: Protein hydrolysate high dose

Protein hydrolysate low dose

EXPERIMENTAL

Dietary Supplement: Protein hydrolysate low dose

Placebo

PLACEBO COMPARATOR

Dietary Supplement: Placebo

Interventions

Protein hydrolysate high dose DIETARY_SUPPLEMENT

Protein hydrolysate high dose

Protein hydrolysate low dose DIETARY_SUPPLEMENT

Protein hydrolysate low dose

Placebo DIETARY_SUPPLEMENT

Placebo

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Healthy individuals (based on their medical history provided during a general health questionnaire)
• Participants are amateur or (semi-) professional athletes in resistance or interval sports (engage in \>6 hours of intense physical activity per week).
• Age 18 - 35
• Experience in resistance training

You may not qualify if:

• Use of creatine supplements and/or anabolic steroids.
• Allergy to test product/protein
• Allergy to specific protein hydrolysate
• BMI lower than 18 or higher than 30.
• Lack of technique in correctly performing a barbell squat (judged by sports physiologist).
• Recent muscle injury in legs or back less than one month before the start of the study.
• Cardiovascular complications
• Use of medication
• Administration of investigational drugs or participation in any scientific intervention study which may interfere with this study (to be decided by the principle investigator), in the 180 days prior to the study.
• Abuse of products; alcohol (\> 20 alcoholic units per week) and drugs

Sponsors & Collaborators

• BioActor: lead

MeSH Terms

Interventions

Protein Hydrolysates

Intervention Hierarchy (Ancestors)

Proteins; Amino Acids, Peptides, and Proteins

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 2, 2017
• First Posted: February 24, 2017
• Study Start: June 6, 2016
• Primary Completion: February 9, 2017
• Study Completion: February 20, 2017
• Last Updated: March 3, 2017

Record last verified: 2017-03