NCT03056443

Brief Summary

The study aimed to examine the effect of Continuous Positive Airway Pressure (CPAP) initiation for newly diagnosed obstructive sleep apnea (OSA) in hospitalized heart failure patients on reducing 30-day hospital readmission rate through a clinical trial.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
13

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2016

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 8, 2016

Completed
1 year until next milestone

First Submitted

Initial submission to the registry

February 13, 2017

Completed
4 days until next milestone

First Posted

Study publicly available on registry

February 17, 2017

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2017

Completed
4.1 years until next milestone

Results Posted

Study results publicly available

February 16, 2022

Completed
Last Updated

February 16, 2022

Status Verified

January 1, 2022

Enrollment Period

1.9 years

First QC Date

February 13, 2017

Results QC Date

November 5, 2021

Last Update Submit

January 25, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • All-cause Hospital Readmission Within 30 Days of Hospital Discharge.

    Thirty-day hospital readmission will be defined as a hospitalization or visit to the emergency department (ED) for a cardiac cause \> 48 h after discharge. A readmission will be defined as a hospitalization for any reason within 30 days after discharge, and only the first readmission will be counted in case of multiple readmission in the 30-day period.

    From hospital discharge to any hospitalization readmission within 30 days from discharge

Study Arms (2)

Continuous Positive Airway Pressure-CPAP

EXPERIMENTAL

CPAP education and discharge with auto-adjusting Continuous Positive Airway Pressure (CPAP) in addition to usual standards of clinical care for heart failure.

Device: Continuous Positive Airway Pressure (CPAP)

Standard of Care

NO INTERVENTION

CPAP initiation per standard of care based on approval by insurance company and DME company with management as per usual standards of clinical care for heart failure.

Interventions

The auto-CPAP group will be scheduled for follow-up with a phone call at 2 - 3 weeks post discharge, then in sleep medicine clinic at 1 month (+2 weeks) and 6 months (+2 weeks) to assess their progress on CPAP.

Continuous Positive Airway Pressure-CPAP

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Hospitalized having a documented history of heart failure
  • Anticipated hospitalization of more than 24 hours
  • Subject has obtained a score of \> 15 on the Ohio Sleep Medicine Institute Preoperative questionnaire.
  • Subject has an apnea-hypopneas index (AHI) of \> 5/h as confirmed by sleep medicine physician

You may not qualify if:

  • The presence of any conditions that the investigator feels will interfere with the use of CPAP

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

West Virginia University

Morgantown, West Virginia, 26506, United States

Location

Related Publications (1)

  • Stansbury R, Abdelfattah M, Chan J, Mittal A, Alqahtani F, Sharma S. Hospital screening for obstructive sleep apnea in patients admitted to a rural, tertiary care academic hospital with heart failure. Hosp Pract (1995). 2020 Dec;48(5):266-271. doi: 10.1080/21548331.2020.1799601. Epub 2020 Aug 4.

MeSH Terms

Conditions

Sleep Apnea, ObstructiveHeart Failure

Interventions

Continuous Positive Airway Pressure

Condition Hierarchy (Ancestors)

Sleep Apnea SyndromesApneaRespiration DisordersRespiratory Tract DiseasesSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System DiseasesHeart DiseasesCardiovascular Diseases

Intervention Hierarchy (Ancestors)

Positive-Pressure RespirationRespiration, ArtificialAirway ManagementTherapeuticsRespiratory Therapy

Results Point of Contact

Title
Robert Stansbury, MD
Organization
West Virginia University

Study Officials

  • Robert Stansbury, MD

    West Virginia University

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor, Sleep Medicine Fellowship Program Director

Study Record Dates

First Submitted

February 13, 2017

First Posted

February 17, 2017

Study Start

February 8, 2016

Primary Completion

December 31, 2017

Study Completion

December 31, 2017

Last Updated

February 16, 2022

Results First Posted

February 16, 2022

Record last verified: 2022-01

Data Sharing

IPD Sharing
Will not share

Locations