Prevalence of Bacteria Following Endodontic Treatment
Prevalence and Phenotype of Oral Enterococcus Faecalis
1 other identifier
observational
200
1 country
1
Brief Summary
Sampling of accessed root canals with endodontic paper points during treatment and immediately pre-obturation of endodontic root canals was carried out.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2013
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 30, 2013
CompletedFirst Submitted
Initial submission to the registry
February 14, 2017
CompletedFirst Posted
Study publicly available on registry
February 16, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 30, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
October 30, 2018
CompletedFebruary 17, 2017
February 1, 2017
4.3 years
February 14, 2017
February 16, 2017
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Detection of residual bacteria during and post root canal treatment
Using a vital fluorescent stain bacteria sampled from the root canal space were detected during and post root canal treatment.
June 2016
Study Arms (2)
Primary treatments
Patients undergoing primary root canal treatments. Only teeth which have not previously been accessed are included in this cohort.The source population are adults aged 18-65, referred by their general dental practitioner into specialist endodontic clinics of Guy's Hospital
Re-treatments
Patients undergoing re-treatments. Only teeth which had a previous root canal treatment which failed are included in this cohort.The source population are adults aged 18-65, referred by their general dental practitioner into specialist endodontic clinics of Guy's Hospital
Interventions
Detection of residual vital bacteria in the root canal space. No intervention, as it is an observational study. Vital bacteria are looked for in the samples taken from the root canal space.
Eligibility Criteria
The source population are adults aged 18-65, referred by their general dental practitioner into specialist endodontic clinics of Guy's Hospital, King's College London Dental Institute. Both single- and multi-rooted non-vital teeth are included in the study
You may qualify if:
- Patients with single or multi-rooted teeth undergoing root canal treatment.
You may not qualify if:
- For certain aspects of the study secondary treatments and vital teeth are excluded.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- King's College Londonlead
- Guy's and St Thomas' NHS Foundation Trustcollaborator
Study Sites (1)
King's College London, Dental Institute, Floor 22, Endodontics
London, London, SE1 9RT, United Kingdom
Related Publications (1)
Herzog DB, Hosny NA, Niazi SA, Koller G, Cook RJ, Foschi F, Watson TF, Mannocci F, Festy F. Rapid Bacterial Detection during Endodontic Treatment. J Dent Res. 2017 Jun;96(6):626-632. doi: 10.1177/0022034517691723. Epub 2017 Feb 1.
PMID: 28530469DERIVED
Study Officials
- PRINCIPAL INVESTIGATOR
Federico Foschi, Dr
King's College London
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Dr
Study Record Dates
First Submitted
February 14, 2017
First Posted
February 16, 2017
Study Start
January 30, 2013
Primary Completion
May 30, 2017
Study Completion
October 30, 2018
Last Updated
February 17, 2017
Record last verified: 2017-02