Efficacy of Peppermint and Green Tea in Malodor

NCT03053882 | Completed

• 1 other identifier: SBMU
• Study Type: interventional
• Target: 88
• Locations: 0 countries
• Sites: N/A

Brief Summary

Background: Herbal remedies can have the role of prevention and control of bad breath Since in the previous studies, therapeutic and antibacterial effect of green tea and peppermint had been proven .we studied and compared the effects of green tea and peppermint mouthwashes on halitosis. Materials and Methods: This single-blind clinical trial study with cross over design total of 88 volunteer dental students who complained bad breath and had organoleptic score (\>= 2) and higher average test scores were enrolled. The students were divided randomly into two groups Green Tea - Peppermint were assigned. Organoleptic test in the baseline, on the 7 day, 14 and 21 measured after rinsing the mouthwashes .As well as the satisfaction of both plants on the last day was considered. Data analysis was performed using tests; Wilcoxon signed rank test, Mann Whithney u, GEE (Generalized Estimating Equation -ordinal logistic regression).

Conditions

Bad Breath

Keywords

mouth wash , green tea , peppermint , bad breath

Outcome Measures

Primary Outcomes (1)

• evaluation of changes in organoleptic score

  0-5 organoleptic scale

  baseline,7 days,14 days,21 days

Secondary Outcomes (1)

• satisfaction of patients

  21 days

Study Arms (2)

green tea and peppermint

ACTIVE COMPARATOR

Other: mouthwash

peppermint and green tea

ACTIVE COMPARATOR

Other: mouthwash

Interventions

mouthwash OTHER

mouthwash containing herbal peppermint or green tea

green tea and peppermint; peppermint and green tea

Eligibility Criteria

• Age: 18 Years - 30 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• organoleptic number equal to or higher 2 no foods (garlic and onion) 48 hours before organoleptic test

You may not qualify if:

• systemic disease
• use of antibiotics during study use of other mouthwash during study

Sponsors & Collaborators

• Shahid Beheshti University of Medical Sciences: lead

MeSH Terms

Conditions

Halitosis

Interventions

Mouthwashes

Condition Hierarchy (Ancestors)

Signs and Symptoms, Digestive; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Biomedical and Dental Materials; Specialty Uses of Chemicals; Chemical Actions and Uses; Cosmetics; Manufactured Materials; Technology, Industry, and Agriculture

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Masking Details: investigator
• Purpose: SUPPORTIVE CARE
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor of Oral Medicine

Study Record Dates

• First Submitted: February 4, 2017
• First Posted: February 15, 2017
• Study Start: January 1, 2015
• Primary Completion: January 1, 2016
• Study Completion: June 1, 2016
• Last Updated: February 15, 2017

Record last verified: 2017-02