NCT03052569

Brief Summary

Expanded access to RXDX-105 will be given to patients with cancers harboring RET alterations who have not received TKIs that target RET alterations, who do not qualify for participation in, or who are otherwise unable to access, an ongoing clinical trial for RXDX-105.

Trial Health

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Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 10, 2017

Completed
4 days until next milestone

First Posted

Study publicly available on registry

February 14, 2017

Completed
Last Updated

April 26, 2019

Status Verified

April 1, 2019

First QC Date

February 10, 2017

Last Update Submit

April 24, 2019

Conditions

Interventions

Oral Capsules

Eligibility Criteria

Sexall
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Diagnosis of advanced cancer with RET alterations
  • Unable to participate in an ongoing RXDX-105 clinical trial
  • Willing and able to provide written, signed informed consent
  • Medically suitable for treatment with RXDX-105

You may not qualify if:

  • Prior treatment with a TKI that has activity against RET alterations
  • Currently enrolled in an ongoing clinical study with any other investigational agent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Www.Ignyta.Com

San Diego, California, 92121, United States

Location

MeSH Terms

Interventions

agerafenib

Study Design

Study Type
expanded access
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 10, 2017

First Posted

February 14, 2017

Last Updated

April 26, 2019

Record last verified: 2019-04

Locations