NCT03041584

Brief Summary

To assess implant outcomes, both clinical and radiological, in a randomized study on guided implant placement after 3-year follow-up, compared to non-guided treatment.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2009

Longer than P75 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2009

Completed
3.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2012

Completed
3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2015

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

January 26, 2017

Completed
8 days until next milestone

First Posted

Study publicly available on registry

February 3, 2017

Completed
Last Updated

February 3, 2017

Status Verified

February 1, 2017

Enrollment Period

3.4 years

First QC Date

January 26, 2017

Last Update Submit

February 1, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Radiographic outcome

    Bone loss in mm

    Change between baseline and 3 Year

Secondary Outcomes (3)

  • probing pocket depth

    Change between baseline and 3 Year

  • bleeding on probing

    Change between baseline and 3 Year

  • plaque

    Change between baseline and 3 Year

Study Arms (6)

Materialise Universal®/ mucosa (Mat Mu)

EXPERIMENTAL
Procedure: Guided placementDevice: Astra Tech TX implant

Materialise Universal®/ bone (Mat Bo)

EXPERIMENTAL
Procedure: Guided placementDevice: Astra Tech TX implant

FacilitateTM/ mucosa (Fac Mu)

EXPERIMENTAL
Procedure: Guided placementDevice: Astra Tech TX implant

FacilitateTM/ bone (Fac Bo)

EXPERIMENTAL
Procedure: Guided placementDevice: Astra Tech TX implant

mental navigation (Mental)

ACTIVE COMPARATOR
Procedure: Non-guided placementDevice: Astra Tech TX implant

pilot-drill template (Templ)

ACTIVE COMPARATOR
Procedure: Non-guided placementDevice: Astra Tech TX implant

Interventions

implant placement with use of guide

FacilitateTM/ bone (Fac Bo)FacilitateTM/ mucosa (Fac Mu)Materialise Universal®/ bone (Mat Bo)Materialise Universal®/ mucosa (Mat Mu)

conventional implant placement

mental navigation (Mental)pilot-drill template (Templ)
FacilitateTM/ bone (Fac Bo)FacilitateTM/ mucosa (Fac Mu)Materialise Universal®/ bone (Mat Bo)Materialise Universal®/ mucosa (Mat Mu)mental navigation (Mental)pilot-drill template (Templ)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Provision of informed consent
  • An age of at least 18 year
  • Extraction socket healing for at least 6 months

You may not qualify if:

  • Unlikely to be able to comply with study procedures
  • History of intravenous bisphosphonate treatment
  • Medical history that makes implant insertion unfavorable
  • Current pregnancy
  • Present alcohol and/or drug abuse
  • Major systemic diseases
  • Untreated, uncontrolled caries and/or periodontal disease
  • History of local irradiation
  • Need for bone grafting and/or sinus lift in the planned implant area

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Periodontist

Study Record Dates

First Submitted

January 26, 2017

First Posted

February 3, 2017

Study Start

January 1, 2009

Primary Completion

June 1, 2012

Study Completion

June 1, 2015

Last Updated

February 3, 2017

Record last verified: 2017-02