NCT03039933

Brief Summary

The overall objective and Primary Aim of this Limited Competition: Small Grant Program (R03) is to address the critical need of identifying and decreasing fear of hypoglycemia, which will be accomplished by conducting a pilot randomized clinical trial to evaluate the efficacy of Blood Glucose Awareness Training, which has been adapted for, but never evaluated in adolescents with Type 1 Diabetes (T1D) and their parents.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
43

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Aug 2016

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2016

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

December 19, 2016

Completed
1 month until next milestone

First Posted

Study publicly available on registry

February 1, 2017

Completed
3.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2020

Completed
Last Updated

September 16, 2021

Status Verified

September 1, 2021

Enrollment Period

4 years

First QC Date

December 19, 2016

Last Update Submit

September 8, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Decrease in scores on the Hypoglycemia Fear Survey

    To address the critical need of identifying and decreasing fear of hypoglycemia, which will be accomplished by evaluating the efficacy of Blood Glucose Awareness Training as compared to treatment as usual.

    Baseline, 3 and 6 months

Study Arms (2)

Fear of Hypoglycemia Intervention

ACTIVE COMPARATOR

Cognitive behavioral therapy based psychological intervention occurring every other week for 12 weeks.

Behavioral: Fear of Hypoglycemia

Treatment As Usual

OTHER

Control group completes questionnaires but does not receive any study intervention. Receives medical care as usual.

Other: Treatment As Usual

Interventions

Participants will receive exposure and response prevention and/or hypoglycemia awareness training.

Fear of Hypoglycemia Intervention

Treatment As Usual

Also known as: Standard of Care
Treatment As Usual

Eligibility Criteria

Age10 Years - 17 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • adolescents aged 10-17 years and their parent(s) or legal guardian;
  • T1D duration \>1 year;
  • insulin pump use \>6 months;
  • agreement of both parent and adolescent to participate in intervention sessions;
  • elevated scores on the Parent Hypoglycemia Fear Survey - Behavior Subscale.

You may not qualify if:

  • developmental disability or reading disorder that prevents understanding of the intervention materials; and
  • non-English speaking adolescents and parents.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Colorado, Denver

Aurora, Colorado, 80045, United States

Location

MeSH Terms

Interventions

TherapeuticsStandard of Care

Intervention Hierarchy (Ancestors)

Quality Indicators, Health CareQuality of Health CareHealth Services AdministrationHealth Care Quality, Access, and Evaluation

Study Officials

  • Kimberly Driscoll, Ph.D.

    University of Colorado, Denver

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 19, 2016

First Posted

February 1, 2017

Study Start

August 1, 2016

Primary Completion

August 1, 2020

Study Completion

August 1, 2020

Last Updated

September 16, 2021

Record last verified: 2021-09

Data Sharing

IPD Sharing
Will not share

Locations