NCT03165786

Brief Summary

This study is being conducted to determine the feasibility of a cognitive behavioral therapy intervention to reduce fear of hypoglycemia and improve glucose levels in young adults with type 1 diabetes.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2016

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 26, 2016

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

May 22, 2017

Completed
2 days until next milestone

First Posted

Study publicly available on registry

May 24, 2017

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 16, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 16, 2018

Completed
7.1 years until next milestone

Results Posted

Study results publicly available

February 3, 2025

Completed
Last Updated

February 3, 2025

Status Verified

January 1, 2025

Enrollment Period

1.2 years

First QC Date

May 22, 2017

Results QC Date

September 13, 2024

Last Update Submit

January 29, 2025

Conditions

Keywords

fear of hypoglycemiaself-managementglycemic controlglycemic variability

Outcome Measures

Primary Outcomes (1)

  • Hypoglycemia Fear Scale Score (HFS_2)

    A reliable and valid psychological scale. It is a 5-point Likert scale \[0-4\], that is summed for a single total continuous scale score. Scores may range from 0-72. Higher numbers indicate greater fear of hypoglycemia.

    12 weeks

Secondary Outcomes (3)

  • Diabetes Self-Management Questionnaire Scale Score (DSMQ)

    12 weeks

  • Glycemic Control, the Average Blood Glucose Over a 2-3 Month Period of Time.

    12 weeks

  • Glycemic Variability

    8 weeks

Study Arms (2)

FREE Group

EXPERIMENTAL

Cognitive behavioral therapy intervention with real-time continuous glucose monitoring.

Behavioral: FREE

Control Group

NO INTERVENTION

Real-time continuous glucose monitoring

Interventions

FREEBEHAVIORAL

Cognitive behavioral therapy with real-time continuous glucose monitoring.

Also known as: CBT
FREE Group

Eligibility Criteria

Age18 Years - 30 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • type 1 diabetes ≥ 1 year
  • receive medical care from an endocrinologist
  • use insulin pump therapy
  • have self-reported fear of hypoglycemia (FOH;screening questionnaire)

You may not qualify if:

  • pregnant or breastfeeding
  • actively treated for a mental health condition
  • have a co-existing chronic illness or taking medications (excluding insulin) that may influence diabetes self-management or glycemic variability

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Illinois at Chicago

Chicago, Illinois, 60612, United States

Location

Results Point of Contact

Title
Pamela Martyn-Nemeth, Professor
Organization
University of Illinois Chicago

Study Officials

  • Pamela Martyn-Nemeth, PhD

    Assistant Professor

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Model Details: Randomized controlled trial
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

May 22, 2017

First Posted

May 24, 2017

Study Start

October 26, 2016

Primary Completion

January 16, 2018

Study Completion

January 16, 2018

Last Updated

February 3, 2025

Results First Posted

February 3, 2025

Record last verified: 2025-01

Locations