NCT03035903

Brief Summary

The goal of this clinical protocol is to perform a randomized crossover study to determine the energy cost of holding the MedGem® device above a person's normal resting metabolic rate (RMR) compared to not holding the MedGem® device.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Feb 2017

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 26, 2017

Completed
4 days until next milestone

First Posted

Study publicly available on registry

January 30, 2017

Completed
14 days until next milestone

Study Start

First participant enrolled

February 13, 2017

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2017

Completed
Last Updated

June 6, 2018

Status Verified

June 1, 2018

Enrollment Period

11 months

First QC Date

January 26, 2017

Last Update Submit

June 1, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • Resting Metabolic Rate (RMR)

    Resting metabolic rate will be assessed via a DeltaTrac Metabolic Cart

    3 hours

Study Arms (2)

Not holding, then holding the MedGem®

EXPERIMENTAL

Subjects will be seated in an armless chair and have a RMR measurement taken while not holding, then holding a MedGem® Indirect Calorimeter.

Device: Not holding, then holding the MedGem®Device: Holding, then not holding the MedGem®

Holding, then not holding the MedGem®

ACTIVE COMPARATOR

Subjects will be seated in an armless chair and have a RMR measurement taken holding, then not holding a MedGem® Indirect Calorimeter.

Device: Not holding, then holding the MedGem®Device: Holding, then not holding the MedGem®

Interventions

Subjects will have a RMR measurement taken first while not holding the MedGem®, and then while holding the MedGem®

Holding, then not holding the MedGem®Not holding, then holding the MedGem®

Subjects will have a RMR measurement taken first while holding the MedGem®, and then while not holding the MedGem®

Holding, then not holding the MedGem®Not holding, then holding the MedGem®

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age between 18-65 y
  • BMI 25-40 kg/m2

You may not qualify if:

  • Diabetes mellitus
  • Current smoker
  • Presently on a weight loss regimen
  • Medications: diabetes, oral steroids, blood pressure drugs, weight loss drugs
  • Claustrophobia
  • Pregnant or breastfeeding
  • Congestive heart failure
  • Chronic kidney disease
  • Pacemaker or other metal implants

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Pennington Biomedical Research Center

Baton Rouge, Louisiana, 70808, United States

Location

Study Officials

  • Eric Ravussin, PhD

    Pennington Biomedical Research Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Executive Director for Clinical Science

Study Record Dates

First Submitted

January 26, 2017

First Posted

January 30, 2017

Study Start

February 13, 2017

Primary Completion

December 31, 2017

Study Completion

December 31, 2017

Last Updated

June 6, 2018

Record last verified: 2018-06

Data Sharing

IPD Sharing
Will not share

The data will be not be shared outside of Weight Watchers and the Investigators listed on the protocol for this study.

Locations