NCT03015142

Brief Summary

There is a clear need in spine surgery to place pedicle screws in the right place in the spine with good accuracy to avoid damage to important structures (spinal cord, nerve roots or vertebral arteries). The objective of the study was to investigate the accuracy of screw placement during spine surgery.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
21

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Nov 2016

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 9, 2016

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

January 2, 2017

Completed
7 days until next milestone

First Posted

Study publicly available on registry

January 9, 2017

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 8, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 8, 2017

Completed
2 years until next milestone

Results Posted

Study results publicly available

September 30, 2019

Completed
Last Updated

March 8, 2022

Status Verified

March 1, 2022

Enrollment Period

11 months

First QC Date

January 2, 2017

Results QC Date

July 22, 2019

Last Update Submit

March 7, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Clinical Accuracy of Pedicle Screw Placement Using New Image-guidance Software

    Clinical accuracy of pedicle screw placements using new image-guidance software assessed by three independent reviewers. Accuracy grading was done per Gertzbein classification. Gertzbein classification: grade 0 = breach 0 mm, grade 1 = breach \< 2 mm, grade 2 = breach 2-4 mm, grade 3 = breach \> 4 mm. Values in the data table represent the percentage of screw placements that were determined accurate by three independent reviewers.

    During surgery, mean 6.71 hours

Secondary Outcomes (9)

  • Procedure Time

    During surgery, mean 6.71 hours

  • Time to Insert Pedicle Screw

    Intraoperative, mean 5.18 hours

  • Length of Hospitalization

    From start of the interventional procedure until hospital discharge, approximately 5.3 days

  • System Usability Score (SUS Score)

    End of all surgeries

  • Patient Radiation Dose

    During surgery, mean 6.71 hours

  • +4 more secondary outcomes

Study Arms (1)

New image-guidance software

Patients in this group had spine surgery with new image-guidance software application.

Device: New image-guidance software

Interventions

Patients in this group had spine surgery with new image-guidance software application

New image-guidance software

Eligibility Criteria

Age16 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients \> 16 years.

You may qualify if:

  • Subject undergoing a spine surgery with pedicle screw placement
  • Subject 16 years of age or older
  • Subject able to give informed consent

You may not qualify if:

  • Subject participating in a potentially confounding device or drug trial during the course of the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Karolinska University Hospital

Stockholm, Sweden

Location

Related Links

MeSH Terms

Conditions

Spinal Diseases

Condition Hierarchy (Ancestors)

Bone DiseasesMusculoskeletal Diseases

Results Point of Contact

Title
Rami Nachabe
Organization
Philips

Study Officials

  • Adrian Elmi-Terander, MD

    Karolinska University Hospital

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 2, 2017

First Posted

January 9, 2017

Study Start

November 9, 2016

Primary Completion

October 8, 2017

Study Completion

October 8, 2017

Last Updated

March 8, 2022

Results First Posted

September 30, 2019

Record last verified: 2022-03

Data Sharing

IPD Sharing
Will not share

Locations