Fetal Pulmonary Artery Acceleration to Ejection Time Ratio (PATET) in the Prediction of Subsequent Development of Respiratory Distress Syndrome (RDS)

NCT03008200 | Completed DMC

• 1 other identifier: KayseriEAH
• Study Type: observational
• Target: 115
• Locations: 0 countries
• Sites: N/A

Brief Summary

Fetal PATET ratio evaluation to predict neonatal RDS

Conditions

RDS

Outcome Measures

Primary Outcomes (1)

• Measurement of fetal pulmonary acceleration time to ejection time ratio via ultrasonography in the 115 pregnant women between 27 to 37 weeks of gestation for prediction of respiratory distress syndrome

  The aim of this study is to obtain the effectiveness of fetal pulmonary artery acceleration time to ejection time ratio in fetal lung maturity evaluation

  Ten months

Study Arms (2)

RDS +

postpartum RDS developed group

Device: ultrasound examination

RDS -

postpartum RDS undeveloped group

Device: ultrasound examination

Interventions

ultrasound examination DEVICE

intrauterine fetal pulmonary artery acceleration time to ejection time ratio measurement via ultrasound

RDS +; RDS -

Eligibility Criteria

• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Pregnant women beyond 27 weeks

You may qualify if:

• pregnant women within the 27 weeks of gestation and beyond

You may not qualify if:

• patients who did not give birth within 3 days after the ultrasonographic doppler examination
• fetuses with Any congenital abnormalities
• amniotic fluid abnormalities
• any chronic maternal diseases or pregnancy complications such as;gestational diabetes mellitus,preeclampsia

Sponsors & Collaborators

• Kayseri Education and Research Hospital: lead

Related Publications (3)

• Schenone MH, Samson JE, Jenkins L, Suhag A, Mari G. Predicting fetal lung maturity using the fetal pulmonary artery Doppler wave acceleration/ejection time ratio. Fetal Diagn Ther. 2014;36(3):208-14. doi: 10.1159/000358299. Epub 2014 Aug 13.

  PMID: 25139576 BACKGROUND

• Azpurua H, Norwitz ER, Campbell KH, Funai EF, Pettker CM, Kleine M, Bahtiyar MO, Malkus H, Copel JA, Thung SF. Acceleration/ejection time ratio in the fetal pulmonary artery predicts fetal lung maturity. Am J Obstet Gynecol. 2010 Jul;203(1):40.e1-8. doi: 10.1016/j.ajog.2010.01.075. Epub 2010 Apr 24.

  PMID: 20417479 BACKGROUND

• Guan Y, Li S, Luo G, Wang C, Norwitz ER, Fu Q, Tu X, Tian X, Zhu J. The role of doppler waveforms in the fetal main pulmonary artery in the prediction of neonatal respiratory distress syndrome. J Clin Ultrasound. 2015 Jul-Aug;43(6):375-83. doi: 10.1002/jcu.22219. Epub 2014 Aug 11.

  PMID: 25110859 BACKGROUND

Study Officials

• Barıs Buke

  Kayseri Education and Research Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Pincipal Investigator

Study Record Dates

• First Submitted: December 20, 2016
• First Posted: January 2, 2017
• Study Start: December 1, 2015
• Primary Completion: September 1, 2016
• Study Completion: September 1, 2016
• Last Updated: January 4, 2017

Record last verified: 2016-12

Data Sharing

• IPD Sharing: Will share