Incidence and Risk Factors of Central Line Catheter Related Thrombosis

NCT03450785 | Completed

• 1 other identifier: 1801-152-922
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

Central venous catheters are frequently used for monitoring haemodynamic status and rapidly delivering fluid therapy during the peri- and postoperative periods. Indwelling central venous catheters are typically used 7-14 days postoperatively for additional monitoring and treatment, but patients may develop asymptomatic catheter-related thrombosis, leading to life-threatening pulmonary embolism and death. Early detection helps to avoid such complications. This prospective observational study investigated the risk factors associated with catheter-related right internal jugular vein thrombosis in pediatric patients. The study enrolled 80 pediatric patients who were scheduled to receive central venous catheter. To detect thrombus formation, Doppler ultrasound examinations from the thyroid cartilage level to the supraclavicular region were used after CVC placement and on each of the following days until the catheter was removed.

Conditions

Central Line Complication

Outcome Measures

Primary Outcomes (1)

• thrombus formation using doppler ultrasound examination of internal jugular vein

  after central venous catheter placement and on each of the following days until the catheter was removed (maximum 5 days)

Interventions

ultrasound examination OTHER

Doppler ultrasound examinations from the thyroid cartilage level to the supraclavicular region were used after CVC placement and on each of the following days until the catheter was removed.

Eligibility Criteria

• Age: Up to 6 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

pediatric patients

You may qualify if:

• pediatric patients who were scheduled to catheterize central venous catheter

You may not qualify if:

• patients who had skin infections on the right side of the neck, making them unsuitable for placement of the catheter via the right side of the neck
• patients who had blood coagulation lesions or bleeding tendencies
• patients with thrombocytopenia
• patients with a history of right internal jugular vein thrombosis
• patients who presented right internal jugular vein thrombosis or stenosis on preoperative Doppler ultrasound examination

Sponsors & Collaborators

• Seoul National University Hospital: lead

Study Sites (1)

Jin-Tae Kim

Seoul, South Korea

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: professor

Study Record Dates

• First Submitted: February 22, 2018
• First Posted: March 1, 2018
• Study Start: March 7, 2018
• Primary Completion: April 8, 2020
• Study Completion: April 8, 2020
• Last Updated: March 4, 2021

Record last verified: 2021-03

Locations

KR (1)